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Antimicrobials > Anitipaludiques > Flashcards

Anitipaludiques Flashcards

1
Q

Les classes

A

Schizonticides electifs

Inhibiteurs des acides nucleique (antimetabolite)

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2
Q

Membred du Groupes de schizonticides

A

Derivé quinoleiques

Derivé artemisinine

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3
Q

Membre du groupe des antimetabolites

A

Antifolates
Naphtoquinones
Antibiotique

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4
Q

Derivé quinoléiques composants

A

Amino 4 quinoleines

Amino-alcool

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5
Q

Exemple d’amino 4 quinoleines

A

Chloroquine

Amodiaquine

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6
Q

Amino-alcools

A

Quinine
Mefloquine
Halofantrine
Luméfantrine

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7
Q

MoA quinoléiques

A

Interferent avec l’utilisation de l’Hb en inhibant de la formation de l’hemozoïne

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8
Q

Hemozoïne

A

Pigment malarique dont la formation characterise la presence de plasmodium

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9
Q

Exemple des derivé de artemesine

A

Artesunate
Artéméther
Dihydroartémisine

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10
Q

MoA derivé Artemisine

A

Interferent avec l’utilisation de l’Hb par liberation de radicaux libres toxiques pour le parasite

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11
Q

Composants antifolates

A

Antifoliques

Antifolinique

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12
Q

Exemple antifolique

A

Sulfamide

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13
Q

MoA antifolique

A

Inhibe la dihydropteroate synthase

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14
Q

Exemple antifolinique

A

Proguanil

Pyrimethamine

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15
Q

MoA antifolinique

A

Inhibe la dihydrofolate reductase

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16
Q

Exemple naphtoquinone

A

Atovaquone

17
Q

MoA atovaquone

A

Inhibiteurs des fxn mitochondrial

18
Q

Ab antimetabolites

A

Tetracycline (doxycycline)

Macrolide (erythromycin,azythromycin,clindamycine)

19
Q

MALARONE =

A

Atovaquone + proguanil

20
Q

COARTEM; RIAMET=

A

Arthemeter+lumefantrine

21
Q

MALACUR

A

Dihydroartemesine + phosphate de piperaquine

22
Q

LAPDAP

A

Chlorproguanil + dapsone

23
Q

SAVARINE

A

Chloroquine + proguanil

24
Q

Nom commercial chloroquine

A

NIVAQUINE

25
Q

Nom commercial proguanil

A

PALUDRINE

26
Q

Proguanil + chloroquine

A

SAVARINE

27
Q

Proguanil + atovaquone

A

MALARONE

28
Q

Quinine + quinidine + cinchonine + cinchonidine

A

QUINIMAX

Antimicrobials (24 decks)

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