Animal models Flashcards

1
Q

advantages for using animals in research

A

Control from birth to death
Control genes
Control living environment

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2
Q

what is the welfare board for animals

A

ensures researchers adhere to ethical guidelines
consists of vets, scientists and members of the public

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3
Q

types of animals typically used in psychology

A

rats., fruit flies, birds, dogs, monkeys

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4
Q

what is involved in animal upkeep guidelines

A

appropriate cage sizes
stimulation and enrichment e.g. playtime
vet checks
housing social animals together

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5
Q

example of human error in animal research

A

Hans selye - injected rats alongside colleagues with medicine or control
all rats developed ulcers
results of poor handling

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6
Q

why may animal research be unreliable

A

Tend to focus on one aspect of a disorder
Can only focus on observable symptoms

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7
Q

what is face validity

A
  • Degree to which animal behaviour mimics human equivalent
  • Often based on DSM criteria
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8
Q

what is the knockout technique

A

rats bred for certain properties
non-functioning gene is then transferred to embryos

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9
Q

how may chronic mild stress be induced in rats

A

Constant lighted room
Wet bedding
Blasting white noise
Foot shocks
Food deprivation

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10
Q

how may single prolonged stress be induced in rats

A

Several hours of restraint
Extended force swim

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11
Q

how may we assess anxiety in an elevated plus maze

A

measure times in two distinct environments
Bright and open runway
Dark and walled runway

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12
Q

what is the defensive burying test

A

Foreign objects within bedding
Time spent burying and number of burying acts measured

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13
Q

how may rats display learned helplessness

A

Continuously shocked on one side and unable to move to other
Once barrier removed they do not try to leave

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14
Q

how does the forced swim test assess depression

A

tests effectiveness of antidepressants
more time spent escaping = more effective

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15
Q

what is the tail suspension task

A
  • Rat suspended from tail
    Assess time taken until animal gives up trying to escape
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16
Q

what is anhedonia

A

Inability to feel pleasure
Lack of interest assessed for rewarding behaviours e.g. sugar water or treats