ANEMIA

Question 1

Decreased RBC, Hb, and Hct; Result in a reduction in the oxygen-carrying capacity of the blood and subsequent hypoxia

Answer 1

Anemia

Question 2

Hypochromia grading; Area of central pallor is one-half of cell diameter

Answer 2

1+

Question 3

Hypochromia grading: Area of pallor is three quarters

Answer 3

3+

Question 4

Hypochromia grading: Area of pallor is two-thirds of cell diameter

Answer 4

2+

Question 5

Hypochromia grading: 4+

Answer 5

Thin rim of hemoglobin

Question 6

Polychromasia grading: Slight

Answer 6

1%

Question 7

Polychromasia grading: 2+

Answer 7

5%

Question 8

Polychromasia grading: 1+

Answer 8

3%

Question 9

Polychromasia grading: 3+

Answer 9

10%

Question 10

Polychromasia grading: 4+

Answer 10

> 11%

Question 11

Numerical scale: Normal appearance of slight variation in erythrocytes

Answer 11

0

Question 12

Numerical scale: only a small population of erythrocytes displays a particular abnormality. the terms INCREASED or FEW would be comparable

Answer 12

1+

Question 13

Numerical scale: Severe increase in abnormal erythrocytes in each microscopic field; an equivalent descriptive term is MANY

Answer 13

3+

Question 14

Numerical scale: More than occasional numbers of abnormal erythrocytes can be seen in a microscopic field: an equivalent descriptive term is MODERATELY INCREASED

Answer 14

2+

Question 15

Numerical scale: The most severe state of erythrocytic abnormality, with the abnormality prevalent throughout each microscopic field; comparable terms are MARKED or MARKED INCREASE

Answer 15

4+

Question 16

RBC indices which refer to the measure of average concentration of hemoglobin

Answer 16

MCHC

Question 17

RBC indices which refer to the measure of average weight of hemoglobin

Answer 17

MCH

Question 18

ROULEAUX GRADING: aggregates of 3-4 RBCs

Answer 18

1+/SLIGHT

Question 19

ROULEAUX GRADING: 3+/MARKED

Answer 19

NUMEROUS AGGREGATES WITH ONLY FEW FREE RBCs

Question 20

ROULEAUX GRADING: aggregates of 5-10 RBCs

Answer 20

2+/MODERATE

Question 21

Derived from RBC histogram; coefficient of variation of the MCV

Answer 21

Red Cell Distribution Width (RDW)

Question 22

RDW is _____ proportional to the degree of anisocytosis

Answer 22

Directly proportional

Question 23

Which of the following is not a computed value by the machine?
A. RBC
B. RDW
C. HCT
D. MCHC

Answer 23

A. RBC

• RDW, HCT, MCHC along MCH are computed values by the machine.
• RBC, WBC, Platelets are directly measured by the machine (counted)

Question 24

Term for size variation

Answer 24

Anisocytosis

Question 25

Term for shape variation

Answer 25

Poikilocytosis

Question 26

Term for hemoglobin content variation

Answer 26

Anisochromia

Question 27

Most preferred collection site for bone marrow examination

Answer 27

Posterior superior iliac crest

Question 28

For bone marrow differential count, at least _____ cells but preferably ______ cells must be counted

Answer 28

at least 500 cells; 1000 cells must be counted

Question 29

Normal M:E ratio is

Answer 29

2:1 - 4:1 OR 3:1

Question 30

Reflects body’s tissue iron storage; first test to become abnormal when iron stores begin to decrease

Answer 30

Serum ferritin

Question 31

Measures the ability of trans ferrin to bind iron; indirect measure of transferrin

Answer 31

Transferrin Iron Binding Capacity (TIBC)`

Question 32

Transferrin saturation formula

Answer 32

TS = Serum Fe X 100/TIBC

Question 33

Increased when Fe is deficient

Answer 33

Free Erythrocyrte protorporphyrin/ZEP (Zinc erythrocyte protoporphyrin)

Question 34

Renal and hepatic function tests: in CKD = Elevated serum _____ and ____ + ______

Answer 34

CKD = Elevated Serum CREATININE and BUN + Anemia

Question 35

Most commonly used RBC indices to evaluate anemia

Answer 35

• MCH
• MCHC

Question 36

Test used to determine the mechanism of anemia, whether if it is due to increased RBC loss or Decreased production

Answer 36

Absolute Reticulocyte count