Anaesthesiology SC001: Is He Fit For Surgery? Pre-operative Assessment Flashcards

1
Q

Peri-operative management in Anaesthesia

A
  1. Pre-operative care
    - Medical optimisation
    - Cardioprotection
  2. Intra-operative
    - Choice of technique / drugs / fluids
  3. Post-operative
    - Analgesia / ICU / Medical therapy

Aim:

  • ↓ Peri-operative morbidity + costs by identifying patients at high risk of developing complications —> these patients may benefit from:
    1. Further testing
    2. Alternative management strategies (Medical / Surgical)
  • Pharmacological intervention
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2
Q

Purpose of pre-operative visit

A

Should be done as soon as decision to surgery is made

  1. Assessment of patient
    - Identification + optimisation of co-morbidities (illness not related to need for surgery)
    - Assessment of risk of surgery / anaesthesia
  2. Rapport + relieve anxiety
  3. Appropriate instructions to patients
    - What will happen
    - Pain management
  4. Facilitates planning of anaesthesia + peri-operative care
    - GA / Regional / Epidural etc.
    - Improvement in outcome
  5. Pre-medication
    - To reduce anxiety
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3
Q

Components of pre-operative visit

A
  1. History (obtained personally / questionnaire)
    Patient assessment:
  2. Co-existing diseases
  3. Medications / other therapies / drug allergies
  4. Specific anaesthetic related issues before
  5. Fasting / associated problems
  6. P/E
  7. Investigations
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4
Q

Medications assessment

A
  1. Identification
  2. Drugs that need to be stopped / modified
    - **Oral hypoglycaemics —> **Switch to Insulin (∵ patient will be fasted before surgery, surgery can trigger stress response —> release catecholamines, glucocorticoid —> causing **hyperglycaemia —> insulin requirement may be ↑ peri-operatively)
    - Anticoagulants (e.g. **
    Warfarin: long duration of action + difficult to reverse —> need to change to something more titratable)
    (- Aspirin?) (Permanent effect on platelet aggregation inhibition, but can be cardioprotective in patients for secondary prevention)
  3. Drugs that may need to be measured
    - Digoxin
    - Anticonvulsants
  4. Recreational drugs
    - may interact with anaesthetic drugs
  5. Oral contraceptives
    - no need to be stopped
  6. Indwelling devices
    - Dentures
    - Prosthetic heart valves
    - Pacemakers
    —> may need prophylactic antibiotics
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5
Q

Specific anaesthetic related issues

A
  1. Previous anaesthetic history / mishaps
  2. Allergies
  3. Family history
  4. Worries / requests
  5. Discussion / Explanation of anaesthetic methods
    - GA / Regional / LA sedation
  6. Consent
  7. Plan for post-operative analgesia
    - PCA, epidural etc.
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6
Q

Fasting

A

Why?
- Less likely to regurgitate / aspirate
—> Gastric volume + content (solid / liquid) + pH
—> affect consequence of aspiration

How long?
- Drinking clear fluids —> 95% emptied in 1 hour —> ∴ **2 hours fasting before considered safe (esp. paediatric)
—> Give **
carbohydrate load 1-2 hours before surgery —> Help mitigate stress response during surgery
- Solids - liquefaction —> emptying highly variable —> ***6 hours recommended

Risk factors for delayed gastric emptying:

  • Trauma, pain, drugs (e.g. opioids)
  • Emergency surgery
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7
Q

Risk

A

Potential that a chosen action / activity (including the choice of inaction) will lead to an undesirable outcome

  • implies that a choice has an influence on the outcome
  • almost any human endeavour carries some risk

Life is risky:
Micromort:
—> 1 in million chance of sudden death: same as flipping a coin 20 times with same outcome
- translate small risks into whole numbers that can be immediately compared
—> e.g. risk of death from GA in emergency operation = 1 in 100,000 —> ***10 micromorts per operation (other examples: skydiving, decorating at home on a high ladder)
—> 1 day in hospital: 75 micromorts

Microlife:

  • ***30 mins of life expectancy = one millionth of your life
  • 2 cigarettes: one microlife lost
  • ***accumulate from day to day —> do not go away
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8
Q

Surgery risk and rewards

A

Risk:

  • Mortality
  • Morbidity
  • Medicolegal
  • Cognitive function (∵ surgical stress response)

Reward:

  • Prevention of mortality (cure for cancer / AAA)
  • Improved QoL (joint replacement / cataract removal)
  • Palliation (bowel obstruction)
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9
Q

How do we make risk based decisions?

A
  • Behavioural + organisation psychology underpin our understanding of risk based decision making
    —> why are we irrationally more scared of sharks / terrorist than we are of motor vehicles / medications?
  • In decision theory: regret (and anticipation of regret) can play a significant part in decision-making, distinct from risk aversion (preferring the status quo in case one becomes worse off)
  • All decision-making must consider **cognitive bias, **cultural bias, ***notational bias
    —> acceptance of obviously wrong answers simply because it is socially painful to disagree (consensus opinion)
    —> herd instinct
  • It is earlier to avoid a personally unnecessary risk but our job is to accept risks, albeit trying to minimise it
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10
Q

Shared decision making

A
  1. Explain the problem in brief and find out what the patient understands
  2. Go through pros + cons of available options including uncertainty
  3. Focus on patients’ values + preferences
  4. Do not judge their decision but understand + ensure it is based on correct information + that they are not put under any undue pressure
  5. Involve friends / family is useful
  6. Sometimes decisions are reached quickly / sometimes they need deferring for more time + more information

Conundrum:
- Do patients (or relatives) really know what is best for them?
- Economics
—> Should we consider financial implications of very high risk surgery
—> How to quantify this?
—> In economically developed counties, the justice system consider a human life “priceless”, thus illegalising any form of slavery

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11
Q

Medicolegal aspect of risk

A
  • Full + frank discussion before procedure
  • Consent
  • Shared decision making does not mean frightening patients with risk
  • It is NOT your risk
  • Mortality / morbidity is not necessarily negligent
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12
Q

Risk assessment

A
  • Aerobic capacity can be estimated by history (e.g. flight of stairs) / directly measured by CPX
  • History of PVD, CVA, CHF, MI, Renal disease (Serum Creatinine >150 umol/L) each independently ↑ risk of during by 1.5 times
  • History of TIA / Angina ↑ risk of dying by 1.2 times
  • Risk of post-operative morbidity is double the risk of post-operative mortality

Cardiopulmonary exercise testing

  • Standard ECG stress test + Metabolic gas exchange analysis
  • Gold standard for assessments of functional capacity
  • Can help determine cause of dyspnea on exertion: Circulatory vs Pulmonary vs Peripheral etiologies
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13
Q

Complications of anaesthesia

A
  • High incidence of peri-operative cardiac morbidity / mortality
    —> 1% MI
    —> 0.3 % CVS deaths
    —> rate will be much higher with operations e.g. vascular surgery
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14
Q

Identification of high risk patients

A
  1. History + P/E
    - Exercise capacity
    - Functional stratus
  2. Surgical procedure?
  3. Risk indices
    - ASA classification
    - Revised Goldman / National surgical quality improvement program database (ACS)
    - Gupta (recent)
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15
Q

American Society of Anaesthesiologist (ASA) classification

A

Very subjective

Identification of high-risk patients
—> predict perioperative risks
—> Correlates well with outcome:
Class 1: A normal **healthy patient
Class 2: Patient with **
mild systemic disease
Class 3: Patient with **severe systemic disease
Class 4: Patient with severe systemic disease that is a **
constant threat to life
Class 5: A moribund patient **not expected to survive without the operation
Class 6: **
Emergency

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16
Q

Functional capacity

A
  • Simple, inexpensive assessment
  • Major determinant of peri-operative risk
  • 1 MET = Exercise consumption of resting adult
  • ***>7 MET without ischaemia = Low risk
  • ***Inability to climb 2 stairs is associated with a PPV of 89% for cardiopulmonary complications
17
Q

Basis for testing

A
  • Evidence-based medicine
    —> systematic review of RCTs e.g. AHA / ACC
  • Bayesian analysis
    —> a test is most useful in a population with a moderate probability (30-70%) of disease
  • Avoid unnecessary, costly, potentially hazardous investigations
  • Poor PPV of non-invasive stress test
  • Considerable risk of coronary angiography / coronary revascularisation —> may not be protective —> ↑ risk of peri-operative MI
    —> apparent risk reducing interventions may paradoxically ↑ risk (e.g. PCI)
    —> may be expensive
  • Peri-operative plaque stabilisation by pharmacological means may be as important in prevention of PMI as an ↑ in myocardial O2 supply / ↓ in myocardial O2 demand
18
Q

Medical therapy for Cardioprotection

A
  1. Aspirin
    - Secondary prevention
    - ↑ bleeding may negate benefits
  2. Beta blockers
    - Continue therapy
    - Probably no benefit from initiation
  3. Statins
19
Q

Diabetes

A
  • Modern epidemic
  • 25% require surgery
  • 5x ↑ peri-operative mortality
  • 2-4x ↑ heart disease / stroke
    —> 65% die from heart disease / stroke
    —> frequently associated with silent ischaemia
    —> risk of PTE ↑ 6x
  • Resistant to pre-conditioning
  • Impaired leukocyte function, including altered chemotaxis + phagocytic activity —> ***risk of infection
  • Glycaemia control improves outcome
    —> but does ***NOT need to be very aggressive / tight (otherwise hypoglycaemic)
    —> 80-150 mg/dL
    —> healing, infection, MI
20
Q

Enhanced Recovery After Surgery (ERAS) program

A

Evidence-based multidisciplinary care pathway aimed at:

  • ↓ length of stay + complications
  • ↓ variability (by standardisation of care, protocols)
  • ↓ cost
  • Improving quality of care
  • Increasing value = Quality divided by Cost

Pre-operative:

  1. Preadmission counselling
  2. No / Selective bowel preparation
  3. Oral fluid (Carbohydrate loading)
  4. No prolonged fasting
  5. Antibiotic prophylaxis
  6. Thromboprophylaxis
  7. No pre-medication

Intra-operative:

  1. Goal-directed fluid therapy
  2. Epidural anaesthesia / analgesia
  3. Short acting anaesthetic agents
  4. Short incision, no drains
  5. Warm air body heating / Maintanance of normothermia (body warmer / warm IV fluid)
  6. Avoidance of Na / fluid overload

Post-operative:

  1. No NG tube
  2. Epidural anaesthesia / analgesia
  3. Prevention of N+V
  4. Avoidance of Na / fluid overload
  5. Early removal of urine catheters
  6. Early oral nutrition
  7. Non-opioid analgesics / Multimodal analgesia (minimise SE of opioid)
  8. Early mobilisation
  9. Stimulation of gut mobility
  10. Audit of compliance
21
Q

Summary

A
  1. Understand relative risk / benefit
  2. Shared decision making
  3. Clinical evaluation + Selective investigation
  4. Simple interventions effective + safe
    - Communication / Team work
    - Time out before surgery
  5. Care pathways are useful
    - ERAS
    - EBPOM