Anaemia in Practice Flashcards

1
Q

what is the symptom when the patient feels pins and needles in their hands and feet?

A

paraesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the anaemia with low Hb and high MCV and low WBC ?

A

megaloblastic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what blood test should be done for megaloblastic anaemia?

A

serum B12/folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what test should be used for pernicious anaemia?

A

anti-intrinsic factor antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the treatment for pernicious anaemia?

A

IM vitamin B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what can’t pernicious anaemic patients be given oral vitamin B12??

A

because they can’t absorb it in the ileum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

state some symptoms of iron deficiency anaemia?

A

difficulty concentrating
irritable
SOB on exercise
looks pale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what investigations should be done for iron deficiency anaemia?

A

low Hb/MCV/MCH
high platelets
ferritin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what cell description is iron deficient anaemia?

A

hypo chromatic microcytic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what questions should be asked for iron deficiency anaemia?

A

menorrhagia
diet
GI symptoms (bleed)
increased requirement (pregnancy)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the Tx for iron deficient anaemia?

A

oral iron and diet advice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the test for hypo chromatic microcytic anaemia?

A

ferritin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the treatment for iron deficient anaemia from suspected GI bleed with chest pain?

A

blood transfusion

- since chest pain may be from critical cardiac ischaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the diagnosis of hypo chromic microcytic anaemia with a normal ferritin ?

A

thalassaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

is thalassaemia autosomal dominant or recessive ?

A

autosomal recessive

- 1 in 4 chances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does a positive DAGT test suggest?

A

an autoimmune haemolysis condition

17
Q

what does a low serum haptoglobin suggest?

A

high haemolysis since it binds to free Hb

18
Q

what does a high bilirubin and LDH suggest?

A

highs haemolysis

19
Q
Noticed yellow, chest pain . SOB on exercise
Low Hb,
High WBC/platelets, 
Normal MCV and MCH
what does this suggest?
A

sickle cell

20
Q

what test should be done to confirm a diagnosis of sickle cell?

A

haemoglobinopathy screen

21
Q

can someone with sickle cell disease have pain from splenic infarction?

A

no

♣ Hyposplenic from very early on in life
♣ Usually only infarcts a very large organ when it outgrows its blood supply