Anaemia and Microcytic anaemia Flashcards
What is an increase in red cell production?
Reticulocytosis
What colour do reticulocytes stain?
Purple / deep red
How does blood film appear with reticulocytes?
Polychromatic
What is measured regarding red blood cells?
Haem conc
Red cell number (conc)
Red cell size (mean cell volume)
What can be calculated regarding red cells?
Haematocrit
Mean cell haem
mean cell haem conc
What else can be tested regarding red cells?
Blood film (cellular morphology) Reticulocyte count (assess marrow response)
What is hypoproliferative?
Reduced amount of erythropoiesis
What is a maturation abnormality?
Eryhtropoiesis present but inneffective
What should you consider when the MCV is low (microcytic)?
Problems with haemoglobinisation
What should you consider when the MCV is high (macrocytic)?
Problems with maturation
What is needed to make haemoglobin?
Globins
Haem
Porphyrin ring
Iron
What does hypochromatic mean?
lacking in colour
What is Thalassaemia?
Globin problem