Amiodarone & Atropine Flashcards
Amiodarone Trade Name:
Cordarone®
Amiodarone Class:
Antidysrhythmic
Amiodarone Standard Supply:
Prefilled syringe
Amiodarone MOA:
-Blocks sodium, potassium & calcium channels
-Prolongs the action potential & repolarization
-Slows the sinus rate
-Increases the PR interval & QT interval
Amiodarone Indications:
-Ventricular fibrillation
-Pulseless Ventricular tachycardia
-Wide complex tachycardia
Amiodarone Contraindications:
-Cardiogenic shock
-Hemodynamically significant bradycardia
-2nd degree & 3rd degree heart block
-Hemodynamically significant hypotension
Amiodarone S/E:
-Bradycardia
-Hypotension
-Heart block
-CHF
-Headache
-Dizziness
-Nausea/vomiting
Amiodarone Routes:
-IV
-IO
-Infusion
Amiodarone Onset:
1-3 min
Amiodarone Adult Dosages:
-Cardiac arrest: 300 mg; IF NO RESPONSE, admin 150 mg over 3-5 min
-Tachydysrhythmias: 150 mg in 50 mL D5W infused over 10 min
-Infusion: 1.0 mg/min
Amiodarone PEDS Dosages:
-Ventricular fibrillation: 5.0 mg/kg; may repeat every 5 min twice
MAX DOSE 300 mg
-Ventricular tachycardia: 5.0 mg/kg over 20 min; may repeat twice
Atropine Sulfate Classes:
-Anticholinergic
-Parasympathetic blocker
-Antidote
Atropine Sulfate Standard Supplies:
-Prefilled syringe
-Vial
Atropine MOA:
-Blocks the action of acetylcholine
-Increases HR
-Reverses the symptoms of cholinergic poisoning
Atropine Indications:
-Hemodynamically significant bradycardia
-Organophosphate poisoning
-Carbamate poisoning
-Nerve agent exposure
Atropine Contraindications:
-Hypersensitivity
-Tachycardia
-Hypothermic hemodynamically significant bradycardia
Atropine S/E:
-Tachycardia
-Palpitations
-Flushed, hot, dry skin
-Dizziness
-Drowsiness
-Confusion
-Anxiety
-Headache
-Dilated pupils
-Blurred vision
-Dry mouth
-Nausea/vomiting
Atropine Routes:
IV
IO
ET
Atropine Onset:
Immediate
Atropine Adult Dosages:
-Hemodynamically significant bradycardia: 0.5 mg; may repeat every 3-5 min to MAX 3.0 mg
-Organophosphate poisoning/carbamate poisoning/nerve agent exposure: 1-4 mg; may double dosage every 5 min
-ET: 2-2.5 mg diluted in 10 mL saline
Atropine PEDS Dosages:
-Hemodynamically significant bradycardia: 0.02 mg/kg; may repeat every 3-5 min to max 1.0 mg in children and 2.0 mg in adolescents
-Organophosphate poisoning/carbamate poisoning/nerve agent exposure: 0.03-0.05 mg/kg every 10-20 min
