Amiodarone & Atropine

Question 1

Amiodarone Trade Name:

Answer 1

Cordarone®

Question 2

Amiodarone Class:

Answer 2

Antidysrhythmic

Question 3

Amiodarone Standard Supply:

Answer 3

Prefilled syringe

Question 4

Amiodarone MOA:

Answer 4

-Blocks sodium, potassium & calcium channels
-Prolongs the action potential & repolarization
-Slows the sinus rate
-Increases the PR interval & QT interval

Question 5

Amiodarone Indications:

Answer 5

-Ventricular fibrillation
-Pulseless Ventricular tachycardia
-Wide complex tachycardia

Question 6

Amiodarone Contraindications:

Answer 6

-Cardiogenic shock
-Hemodynamically significant bradycardia
-2nd degree & 3rd degree heart block
-Hemodynamically significant hypotension

Question 7

Amiodarone S/E:

Answer 7

-Bradycardia
-Hypotension
-Heart block
-CHF
-Headache
-Dizziness
-Nausea/vomiting

Question 8

Amiodarone Routes:

Answer 8

-IV
-IO
-Infusion

Question 9

Amiodarone Onset:

Answer 9

1-3 min

Question 10

Amiodarone Adult Dosages:

Answer 10

-Cardiac arrest: 300 mg; IF NO RESPONSE, admin 150 mg over 3-5 min

-Tachydysrhythmias: 150 mg in 50 mL D5W infused over 10 min

-Infusion: 1.0 mg/min

Question 11

Amiodarone PEDS Dosages:

Answer 11

-Ventricular fibrillation: 5.0 mg/kg; may repeat every 5 min twice
MAX DOSE 300 mg

-Ventricular tachycardia: 5.0 mg/kg over 20 min; may repeat twice

Question 12

Atropine Sulfate Classes:

Answer 12

-Anticholinergic
-Parasympathetic blocker
-Antidote

Question 13

Atropine Sulfate Standard Supplies:

Answer 13

-Prefilled syringe
-Vial

Question 14

Atropine MOA:

Answer 14

-Blocks the action of acetylcholine
-Increases HR
-Reverses the symptoms of cholinergic poisoning

Question 15

Atropine Indications:

Answer 15

-Hemodynamically significant bradycardia
-Organophosphate poisoning
-Carbamate poisoning
-Nerve agent exposure

Question 16

Atropine Contraindications:

Answer 16

-Hypersensitivity
-Tachycardia
-Hypothermic hemodynamically significant bradycardia

Question 17

Atropine S/E:

Answer 17

-Tachycardia
-Palpitations
-Flushed, hot, dry skin
-Dizziness
-Drowsiness
-Confusion
-Anxiety
-Headache
-Dilated pupils
-Blurred vision
-Dry mouth
-Nausea/vomiting

Question 18

Atropine Routes:

Answer 18

IV
IO
ET

Question 19

Atropine Onset:

Answer 19

Immediate

Question 20

Atropine Adult Dosages:

Answer 20

-Hemodynamically significant bradycardia: 0.5 mg; may repeat every 3-5 min to MAX 3.0 mg
-Organophosphate poisoning/carbamate poisoning/nerve agent exposure: 1-4 mg; may double dosage every 5 min
-ET: 2-2.5 mg diluted in 10 mL saline

Question 21

Atropine PEDS Dosages:

Answer 21

-Hemodynamically significant bradycardia: 0.02 mg/kg; may repeat every 3-5 min to max 1.0 mg in children and 2.0 mg in adolescents
-Organophosphate poisoning/carbamate poisoning/nerve agent exposure: 0.03-0.05 mg/kg every 10-20 min