Aminoglycosides Flashcards
1
Q
Examples of aminoglycosides
A
Gentamicin
Streptomycin
Neomycin
2
Q
What is the MOA of aminoglycosides
A
Binds to the 30s and cause a misreading in the MRNA
3
Q
Aminoglycosides can be bacteriocidal or bacteriostatic depending on the
A
Dosage
4
Q
Uses/Indications of aminoglycosides
A
Gram negative bacilli like enterobacteriace
Aerobic bacilli
5
Q
What aminoglycosides is used to prepare the bowel for colorectal surgery
A
Neomycin
6
Q
Almost all aminoglycosides are administered parenterally except
A
Neomycin
7
Q
Adverse effects of aminoglycosides
A
Ototoxicity: enter endolymph and perilymph causing hearing loss in pregnant women…and in fetus
Nephroticicity
