Alveolar Ventilation and Perfusion Flashcards
what is the leading cause of low blood oxygen
-V/Q inequality
PaO2 level that is hypoxemia
- <80 mmHg
the total pressure of a mixture of gasses is the sum of
- the partial pressures exerted by each gas
what is conditioning?
- warming, cleansing, and humidifying inspired air
what is the partial pressure of water vapor
- 47 mmHg
what happens when you introduce water vapor into a mixture of dry gases
- dry gas partial pressure falls accordingly
what does the blood deliver to the lungs
- CO2
what do the lungs give to the blood
- O2
what is alveolar ventilation
- volume of air reaching alveoli to participate in gas exchange x respiratory rate
the first 150 mL of air that is inspired is
- expired air from the previous breath
amount of CO2 produced by the body’s metabolism per minute compared to the amount of CO2 eliminated by alveolar ventilation - during steady state
- equal
relationship between alveolar ventilation and PACO2
- inverse
increased PaCO2 will result in at change in pH
- fall in blood pH
can doubling ventilation double PAO2
- no
- cannot rise higher than PO2 of humidified air (150)
regulation of ventilation by the CNS is driven primarily by
- arterial PCO2
hyperpnea
- increase in rate and depth of alveolar ventilation caused by a rise in metabolism
tachypnea
- rapid, shallow breathing to maintain sufficient gas exchange
apnea
- cessation of breathing
hypoapnea
- slow, shallow breathing
PaCO2 of hyperventilation
- less than 35 mmHg
PaCO2 of hypoventilation
- greater than 45 mmHg
if the lung is functioning perfectly, what will be the partial pressures of gas in the pulmonary blood versus alveolar gas
- equal
what does the A-a difference compare
- calculated PAO2 and PaO2
partial pressure of CO2 in alveolar gas versus that in the arterial blood
- equal
in a subject standing or sitting upright, where is ventilation greatest
why?
- base of the lung
- gravity pulls lung downward and creates more negative interpleural pressure at the apex that holds alveoli more open
at end expiration, which alveoli are held more open
- alveoli at top of lung