Alterations in BP exam 3 (slide show 3) Flashcards
what are some determinates of systemic bp?
- cardiac output (CO)
- resistance to the ejection of blood from the heart
- BP = CO X SVR (systemic vascular resistance
what 3 factors is cardiac output determined by?
- preload
- contractability
- afterload
define cardiac output
- amount of blood that the heart can pump out per min
what is the equation for cardiac output?
- CO = SV (stroke volume) x HR
what is stroke volume?
- volume of blood ejected during each ventricular contraction
- amount of blood that gets out of the heart in 1 ventricular contraction
- another def: per HB how much blood goes out or the force of it
what is SVR
- systemic vascular resistance
define SVR?
- resistance to blood flow offered by all the systemic vasculature, excluding the pulmonary vasculature
- Systemic Vascular Resistance (SVR) is kind of like that. It’s how hard your heart has to push to get blood through all those tiny tubes (blood vessels). If the tubes are wide, blood flows easily. But if they get narrow, the heart has to push harder to get the blood through.
what determines the SVR?
- radius (size) of arteries and degree of vessel compliance
what is pre load?
- amount if blood in the ventricles at the end of diastole
- how much blood gets poured into the heart during relaxation
what is afterload ?
- pressure AGAINST your heart has to fight when pumping the blood
define contractility
- represents innate ability of the heart muscle to contract
when does preload increase?
- hypervolemia
- regulation of cardiac valves
- heart failure
what makes afterload?
- HTN
- vasoconstriction
what increases when afterload increases?
- cardiac workload bc the pressure that the heart has to fight
what is systolic blood pressure?
- peak pressure during cardiac systole (heart contraction)
what effects systolic blood pressure the most?
- SV is the primary factor influencing systolic pressure (strove volume)
what is diastolic blood pressure?
- lowest pressure during cardiac diastole (heart relaxation)
what is the major determinant of diastolic pressure?
- SVR is the major determinant of diastolic pressure (systemic vascular resistance)
what is the first response to changes in BP
- mediated through the sympathetic nervous system as it releases catecholamines
define catecholamines
- category of substances released as the SNS
what detects the changes in BP
- baroreceptors and chemoreceptors
what triggers vasoconstriction?
- catecholamines activates alpha 1 receptors in smooth muscle of arterioles
what in triggers the increases heart rate?
- catecholamines activates beta 1 receptors of the heart to increase heart rate
what does the parasympathetic nervous system do
- slows the heart rate