Allosomal Disorders Flashcards
Inherited disorders which are related to sex chromosome
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
Allosmal disorder
referred to as sex chromosomes
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
Allosomes
More common in females than in males, or in some cases, affect only females.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Dominant disorder
Causes the phenotype to be always expressed in the male.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Recessive disorder
A mutation can only be passed from father to son because only males have a Y chromosome
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
Y-Linked disorders
Affected male inherits trait from heterozygote or homozygote mother.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Recessive disorder
A type of sex-connected inheritance wherein a recessive trait is genetically transposed through a sole gene on the y chromosome.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
Y-Linked disorders
High rates of miscarriage due to early lethality in males.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Dominant disorder
Females with one copy of the mutated gene are carriers
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Recessive disorder
Much more severe effects in males than female heterozygotes.
CHOICES:
X-Linked Recessive disorder, X-Linked Dominant disorder, Allosomes, Allosmal disorder, Y-Linked disorders
X-Linked Dominant disorder
X-Linked Dominant disorders are passed from male to all daughters but not to sons, hence, do not show father-to-son transmission. True or False
True
a genetic condition that affects the skin and other body systems.
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Incontinentia pigmenti (IP)
An X-linked dominant disorder characterized by intracytoplasmic vacuoles containing autophagic material and glycogen in cardiac and skeletal muscle cells in patients with cardiomyopathy and skeletal myopathy, with or without conduction defect.
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Danon disease
Rare X-linked dominant disorder that is associated with seizures and mental retardation.
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Incontinentia pigmenti (IP)
Caused by mutations in the X- linked MECP2 (Methyl CpG Binding Protein 2) gene
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Rett Syndrome
Caused by mutation in the LAMP2 (Lysosome- associated membrane protein 2) gene
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Danon disease
It is caused by mutations in the IKBKG (Inhibitor of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma) gene
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Incontinentia pigmenti (IP)
Most common genetic cause of severe intellectual disability in females
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Rett Syndrome
Wolf-Parkinson-White (WPW) syndrome, visual acuity abnormalities due to choriocapillaris ocular atrophy, or mental retardation
CHOICES: Incontinentia pigmenti (IP), Danon disease, Rett Syndrome
Danon disease