Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pediatrics Rotation > Allergy and Immunology > Flashcards

Allergy and Immunology Flashcards

1
Q

Anaphylaxis

A

systemic IgE mediated reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

treatment for anaphylaxis

A

epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Allergic rhinitis

A

IgE-medicated inflammatory response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Allergen-specific IgE binds to what

A

mast cells and basophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dennie’s lines

A

creases under eyes as a result of chronic edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

nasal smear for cytology for allergic rhinitis sows

A
  • more than 10 percent eosinophils

- polymorphic leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most effective class of drugs for allergic rhinitis

A

intranasal steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

first line therapy for allergic rhinitis

A
  • first generation antihistamin

- second generation: safer and better tolerated, not as effective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

why are decongestants used for a short period of time in allergic rhinitis

A

side effects of insomnia, nervousness, and rebound rhinitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

principle of immunotherapy of repeated injection so what for allergic rhinitis

A

allergens,

- with time, better tolerance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

atopic dermatitis

A

eczema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

lichenification

A

thickening of skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

chronic changes to atropic dermatitis

A

lichenification and pigmentary changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

infantile form of atopic dematitis

A

truncal and facial areas
along scalp
extensor surfaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

early childhood atopic dermatitis

A

flexural surfaces
chronic itching
lichenification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Diagnosis for atopic dermatitis

A

3/4

  1. pruritus
  2. personal or family history of atopy
  3. typical morphology and distribution
  4. relapsing or chronic dermatitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

management of atopic dermatitis

A

antihistamines

steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

most common food allergies

A 
egg
milk 
peanut
soy 
wheat 
fish
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

laboratory test for food allergy

A

skin test

radioallergosorbent (RAST) test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how can diffuse urticaria be treated

A
  • antihistamines

- steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Urticaria

A

circumscribed, raised, evanescent (vanishing) areas of edema that are almost always pruritic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

patients with chronic urticaria have what problem

A

IgG antibody to IgE receptor

23
Q

latex allergy can cause what

A

acute urticaria

24
Q

drug allergy

A

IgE mediated or direct mast cell degranulation

25
Q

Innate response of body

A
  • phagocytic cells
  • natural killer cells
  • toll-like receptors
  • mannose-binding protein
  • alternative pathway of complement
26
Q

adaptive immune response

A

B and T cells

27
Q

Most common immune deficiency

A

IgA deficiency

28
Q

Management of IgA deficiency

A

manage infections

29
Q

Common variable immunodeficiency

A

defect in B-cell maturation

30
Q

Management of Common variable immunodeficiency

A

IVIG
aggressive management of infections
chronic diarrhea management

31
Q

Severe combined immunodeficiency disease

A

defective T and B cells

32
Q

how is SCID inherited

A

X-linked

AR

33
Q

clinical feature of SCID

A

FTT
chronic diarrhea
infections within first few months

34
Q

Management of SCID

A
  • no blood products
  • monthly IVIG
  • P. carinii pneumoni prophylaxis
35
Q

Ataxia telangiectasia

A

AR
Cerebellar ataxia
oculocutaneous telangiectasias

36
Q

what chromosome is ataxia telangiectasia on

A

11

37
Q

what management should be avoided in ataxia telangiectasia

A

ionizing radiation

38
Q

Wiskott-Aldrich syndrome

A

WATER
Thrombocytopenia
Eczema
Recurrent infections

39
Q

how is Wiskott-Aldrich syndrome inherited

A

X-linked

-short arm

40
Q

Wiskott-Aldrich syndrome are susceptible to what infections

A

encapsulated organisms

41
Q

which antibody is low for Wiskott-Aldrich syndrome

A

IgM

42
Q

Management Wiskott-Aldrich syndrome

A

HLA-matched bone marrow transplant
IVIG
splenectomy

43
Q

what must be given regularly after splenectomy

A

prophylactic antibiotics or IVIG

44
Q

Bruton’s Agammaglobinemia

A

Bad B

Good T

45
Q

What gene is impacted in Bruton’s Agammaglobinemia

A

BTK gene

46
Q

Bruton’s Agammaglobinemia increases susceptibility to what infections

A

encapsulated bacteria

47
Q

Management of Bruton’s Agammaglobinemia

A

monthly IVIG replacement

48
Q

Chronic Granulomatous Disease

A

deficient NAPDH oxidase

49
Q

Diagnosis for Chronic Granulomatous Disease

A

nitroblue tetrazolium

flow cytometric assay

50
Q

Schwachman-Diamond syndrome

A
  • decrease neutrophil chemotaxis
  • cyclic neutropenia
  • pancreatic exocrine insufficiency
51
Q

clinical features of Schwachman-Diamond syndrome

A
  • recurrent soft tissue infection
  • chronic diarrhea
  • FTT
52
Q

Chediak-Higashi syndrome

A

neutropenia and thrombocytopenia

  • S. aures common infection
  • partial oculocutaneous albinism
53
Q

deficiency or dysfunction of C1 esterase inhibitor causes

A

hereditary angioedema

Pediatrics Rotation (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions