allergy

Question 1

IgE mediated reactions
early
late

Answer 1

early phase is histamine release - MAST cells

late: 4-6 hours: nasal congestion cough and bronchospasm

Question 2

hypersensitivity defn

Answer 2

reproducible symptoms / signs following exposure to a defined stimulus at a dose that is usually tolerated

Question 3

allergy

Answer 3

hypersensitivity reaction by specific immunological mechanisms

ige / non ige (coeliac)

Question 4

anaphylaxis triad

Answer 4

Bronchial, laryngeal, cardiovascular involevement

a serious allergic reaction w bronchial, laryngeal and cvd involvement that is both rapid and may result in death

Question 5

chronic untreated asthma can have what type of chest sign on examination?

Answer 5

hyperinflated chest

Question 6

mild acute allergic reaction signs

Answer 6

uriticaria
facial swelling

Question 7

severe reaction

Answer 7

wheeze
stridor
abdo pain
diarrhoea
shock
collapse

Question 8

food intolerence?

Answer 8

non immune hypersensitive reaction

Question 9

ige mediated best investigation?

Answer 9

skin prick tests

Question 10

measurement of IgE antibodies

Answer 10

greater the number the more the alergy

Question 11

mx of allergies?

Answer 11

avoidance of specific food
educate
plans / training
mild mx : antihistamines
severe: IM adrenaline (epipen)

Question 12

allergic rhinitis?

Answer 12

oral antihistamine

Question 13

what is allergic rhinitis?
what complication can occur
how to manage?

Answer 13

chronic inflammation
type 1 hypersentivity

nasal polyps (intranasal corticosteroids for this) beclometasone

sneeze: oral antihistamine / steroid