Allergic reactions to drugs and anaphylaxis Flashcards
1
Q
HYpersensitivity
A
Objectively reproducible symptoms or signs, initiated by exposure to a defined stimulus at a dose tolerated by normal subject’s and may be caused by immunologic (allergic) and non-immunologic mechanisms
2
Q
Type 1 hypersensitivity
A
IgE mediated drug hypersensitivity
3
Q
Type 2 hypersensitivity
A
IgG mediated cytotoxicity
4
Q
Type 3
A
Immune complex deposition
5
Q
Type 4
A
T cell mediated
6
Q
Type 1 (acute anaphylaxis)
A
Prior exposure to antigen/drug
7
Q
Which symptoms are needed for the reaction to be classified as anaphylaxis?
A
Problems with Airway/ Breathing / Circulation
8
Q
D in ABCDE stand for
A
9
Q
E in ABCDE stand for
A
Exposure
10
Q
How to help
A
Remove trigger if possible
Lie patient flat
For pregnant ladies, lie on left side for venous return
11
Q
A
