Alkaloids 2 - Part 1 Flashcards
Sources of Strychnine and Brucine
Nux vonica
Scientific name for Nux Vonica
Strychnos nux vonica
Nux vonica is closely related to?
Strychnos ignatii
Strychnos ignatii is the commercial source of? (2)
Strychnine
Brucine
Strychnine is commonly marketed as? (2)
Strychnine sulfate
Strychnine Phosphate
Brucine is less toxic than _________ and is used commercially as __________
Strychnine
Alcohol Denaturant
Brucine is extremely _________
Bitter
Strychnine is extremely _________ and is used as an ________
Toxic
Central Stimulant
Strychnine fatal dose is _______ and can be used as a __________
60-90 mg
Vermin Killer
Alkaloid that results in tonic convulsions
Strychnine
What are the other names of Physostigma Bean?
Calabar Bean
Ordeal Bean
Physostigma bean is from the dried seeds of
Physostigma venenosum
% yield of Physostigma Alkaloid
not less than 0.15%
in 1846 __________ described the uses of seeds known as _______ by the natives of old Calabar
Darniell
Esere
Alkaloids found inCalabar (Physostigma) bean (4)
Physostigmine (Eserine)
Eseramine
Geneserine
Physovenine
Where is Physostigmine (Eserine) obtained?
Dried ripe seeds of Physostigma venenosum
Use of Physostigmine (Eserine)
Reversable inhibitor for cholinesterases
Treatment for Glaucoma
Indole Alkaloid in topical 0.25% form that is used to treat conjunctiva
Physostigmine sulfate
Eserine sulfate
Other names for Ergot
Rye Ergot
Secale Cornutum
Former term for ergot
Dried sclerotium
Required % yield for ergot
0.15%
Common name for ergot
Spurred rye
It has been grown saprophytically in submerged culture
Claviceps paspali
Accepted chemical name of isolysergic acid isomer of ergonovine
ergometrinine
