Adrenergic and Cholinergic Drugs

Question 1

What are the 2 neurotransmitters involved in the ANS?

Answer 1

acetylcholine- cholinergic
norepinephrine- adrenergic or noncholinergic

Question 2

What are the two categories of cholinergic receptors?

Answer 2

nicotinic, muscarinic

Question 3

What are the categories of adrenergic receptors (5)?

Answer 3

Alpha-1, Alpha-2, Beta-1, Beta-2, Beta-3

Question 4

Fill in the correct adrenergic receptor to its site:

____: adipose tissue, heart, bladder
_____: found on smooth mm, bronchioles, uterus, bladder
_____: found in smooth mm
_____: in heart and in kidneys
_____: decrease the release of norepinephrine

Answer 4

Beta-3
Beta-2
Alpha-1
Beta-1
Alpha-2

Question 5

Beta-1 antagonist drug will block the Beta-1 receptor which will cause a ____ of the HR and ____ myocardial contractility

Answer 5

slow, decrease

Question 6

Anticholinergic drugs will _____ synaptic activity

Answer 6

decrease

Question 7

___ acting stimulants bind to the cholinergic receptor and ____ it

Answer 7

direct, activate

Question 8

_____ acting stimulants ___ the activity at cholinergic synapses by ____ the acetylcholinesterase enzyme

Answer 8

indirect, increase, inhibiting

Question 9

What are some adverse effects of cholinergic stimulants?

Answer 9

GI distress, increased salivation, bronchoconstriction, bradycardia, difficulty in visual accommodation, increased sweating

Question 10

Which anticholinergic drugs are very specific for the nicotinic receptor in the autonomic ganglia and are used to treat HTN, and block the neuromuscular junction?

Answer 10

antinicotinic

Question 11

Which anticholinergic drugs are more common and used primarily to treat GI disorders and may be used for Parkinson disease, cardiovascular system, motion sickness, preoperative medications?

Answer 11

antimuscarinic

Question 12

What are common side effects of anticholinergic drugs?

Answer 12

blurred vision, urinary retention, constipation, dry mouth, tachycardia

Question 13

Which type of adrenergic drug is located mostly on smooth mm and helps treat hypotension and nasal congestion and decrease HR during supraventricular tachycardia?

Answer 13

alpha-1 selective agonists

Question 14

Which adrenergic drugs are located mostly in brain and SC CNS synapses and are used to treat hypertension and spasticity?

Answer 14

alpha-2 selective agonists

Question 15

Which adrenergic drug is located in the myocardium is used to increase cardiac output in emergency situations and in short term management of CHF?

Answer 15

Beta-1 selective agonists

Question 16

Which adrenergic drug is located on bronchiole smooth mm and used to treat spasms and constriction associated with asthma, bronchitis, and emphysema?

Answer 16

beta-2 selective agonsists

Question 17

Adrenergic antagonists that bind to adrenergic receptors and BLOCK THEM are referred to as ______ drugs

Answer 17

sympatholytic

Question 18

Which adrenergic drug is used to treat HTN by decreasing peripheral vascular resistance?

Answer 18

alpha (adrenergic) antagonists

Question 19

what is a side effect to be aware of when someone is taking an alpha antagonist?

Answer 19

reflex tachycardia (BP decreasing may cause body to compensate and increase HR as a result leading to orthostatic hypotension)

Question 20

Which adrenergic drug is used to treat HTN, arrhythmias, angina pectoris, s/p MI, CHF and being to beta-1 receptors located on the heart?

Answer 20

beta blockers

Question 21

beta blockers cause an ___ in contractility of the heart and ___ in HR

Answer 21

decrease in both

Question 22

t/f, you can use HR max when treating a patient on a beta blocker

Answer 22

false, use RPE scale instead

Question 23

a pt who has respiratory problems should use a _____ _______ and NOT a non-selective beta blocker

Answer 23

beta-1 antagonist

Question 24

What are common side effects of someone on a beta blocker?

Answer 24

excessive depression of cardiac function
orthostatic hypotension
depression, lethargy, and sleep disorders
blunted HR response to exercise