Adrenergic Agonists

Question 1

Epinephrine

Answer 1

A1=A2; B1=B2

Question 2

Norepineprine

Answer 2

A1=A2; B1>B2

Question 3

Isoproterenol

Answer 3

Beta agonist

• used in emergency for cardiac support (increase HR, strength of contraction)
• watch because B2 dilation of blood vessels (diastolic will drop - low BP)

Question 4

Dopamine

Answer 4

D1>B1>B2>Alpha

• D1 on vasculature in the kidney (cause dilation)
• prevents renal ischemia in shock
• also stimulating B1 (heart)
• very good emergency drug

Question 5

Doputamine

Answer 5

B1>B2>Alpha

- B1 (cardiac support)

Question 6

Phenylephrine

Answer 6

A1>A2»Beta

• A1 vasculature constriction
• increase systemic BP

Question 7

Xylazine

Answer 7

A2>A1»Beta

• A2 (pre-ganglionic reducing neuronal excitability and adrenergic neural transmission)
• sedation

Question 8

Clenbuterol & Terbutaline

Answer 8

B2>B1»Alpha

• asthma (bronchiole relaxation) or to prevent early labour
• relax smooth muscle
• dilate arteries (not great)
• systemic can increase HR