adrenals Flashcards
primary adrenal failure: list the causes, clinical features and explain the management of primary adrenal failure
1
Q
name of primary adrenal failure
A
Addison’s
2
Q
Addison’s disease: causes
A
autoimmune disease where immune system wipes out corte, or tuberculosis of adrenal gland
3
Q
Addison’s disease effect on cortisol
A
cortisol deficiency
4
Q
Addison’s disease effect on pituitary
A
pituitary starts secreting lots of ACTH as no negative feedback and hence MSH
5
Q
effect of high MSH
A
lots of pigmentation, vitiligo may be present
6
Q
Addison’s disease effect on aldosterone
A
loss of aldosterone
7
Q
effect of loss of aldosterone
A
hypotension, salt loss especially Na+
8
Q
Addison’s treatment
A
rehydrate with normal saline; give dextrose to prevent hypoglycaemia (glucocorticoid deficiency); give hydrocortisone (another glucocorticoid) then prednisolone
