ADRENALINE Flashcards
PHARMACOLOGY OF ADRENALINE
A naturally occurring alpha and beta-adrenergic stimulant.
PRESENTATION OF ADRENALINE
1 mg in 1ml (Glass Ampoule, 1:1000)
1mg in 10ml Glass Ampoule 1:10,000
ACTIONS OF ADRENALINE
6 actions list them all
- Increases HR by increasing SA node firing rate (Beta 1)
- Increases conduction velocity through AV node (Beta 1)
- Increases myocardial contractility (Beta 1)
- Increases irritability of the ventricles (Beta 1)
- Causes bronchodilation (Beta 2)
- Causes peripheral vasoconstriction (Alpha)
CONTRAINDICATIONS OF ADRENALINE
Hypovolaemic shock without adequate fluid replacement
PRECAUTIONS OF ADRENALINE
List all 4
- Elderly patients
- Pts with cardiovascular disease
- Pts on monoamine oxidase inhibitors
- Pts on Beta blockers as higher doses may be required
PRIMARY EMERGENCY INDICATIONS OF ADRENALINE
List all 10
- Persistant VF or unconscious, pulseless, VT
- Asystole
- PEA
- Inadequate perfusion (Cardiogenic)
- Inadequate perfusion (Non-cardiogenic - non hypovolaemic)
- Anaphylaxis
- Severe asthma
- unconscious asthma with no recordable BP
- Croup
- Bradycardia with poor perfusion
ROUTE OF ADMINISTRATION OF ADRENALINE
- IV
- IM
- ETT
- NEBULISED
- IV INFUSION
- IO
SIDE EFFECTS OF ADRENALINE
List all 7
- Sinus Tachycardia
- Supaventricular arrhythmias
- Ventricular arrhythmias
- Hypertension
- Pupillary dilatation
- May increase size of MI
- Feeling of anxiety/palpitations in the conscious Pt
ONSETS & DURATION OF ADRENALINE
IV EFFECTS
Onset: 30 sec
Peak: 3 - 5 min
Duration: 5 - 10 min
IM EFFECTS
Onset: 30 - 90 sec
Peak: 4 - 10 min
Duration: 5 - 10 min
ADRENALINE USE FOR ADULTS & DOSES
Cardiac arrest: 1 mg @ 3/60 IV
Anaphylaxis: 0.3 mg @ 5/60 IM
Asthma: 0.3 mg @ 20/60 IM (X3 max)
ADRENALINE USE FOR PAEDIATRICS & DOSES
Anaphylaxis: 0.01mg/kg @5/60 IM
Asthma: 0.01mg/kg @20/60 IM ( X3 max)
