Adenotonsillar Disease Flashcards
describe general tonsil histology
luminal surface of the tonsil is covered by stratified squamous epithelium, which deeply invaginates the tonsil forming crypts
the base of the tonsil is separated from underyling muscle by a dense collagenous hemi-capsule
the parenchyma contains numerous lymphoid follicles dispersed just beneat the epithelium of the crypts
describe adenoid histology
deep folds and few crypts
surface is composed of ciliated pseudostratified columnar epithelium which functions in mucociliary clearance
deep to surface lies stratified squamous layer followed by transitional layer (responsible for antigen processing)
what happens to the adenoid layers with chronic infection
ciliated pseudostratified columnar epithelium is thinned, resulting in stasis of secretions and increased exposure of the tissue to antigenic stimuli
stratified squamous is thickened
describe tonsil histology
10-30 deep crypts
specialised squamous
lymphoid follicules
clinical features of acute viral tonsillitis
- able to undertake normal activity?
- duration?
sore throat ± lymphadenopathy
malaise
temperature
able to undertake normal activity
lasts 3-4 days
which lymph nodes are often enlarged in tonsillitis
jugulo-diagastric - palatine tonsil drains here first
clinical features of bacterial tonsillitis
- able to undertake normal activity?
- duration?
systemic upset
fever
odonyphagia
halitosis
unable to work/school
lymphadenopathy
lasts around a week and requires ABx to settle
causes of viral tonsillitis
- Rhinovirus, influenza, parainfluenza, enterovirus, adenovirus
causes of bacterial tonsillitis
often caused by Group A Streps eg Strep Pyogenes
also, staphs, Moraxella catarrhalis, mycoplasma, chlamydia, haemophilus
should suspected bacterial cases be swabbed
no - superficial swabs are irrelevant and can lead to over diagnosis
management
paracetamol and Difflam gargle if severe
ABx management?
most cases are viral
but if ill or Centor criteria positive, give penicillin
erythromycin if allergic
which ABx must not be given
amoxicillin
EBV is a DD, and this will cause a rash in those whose pharyngitis is due to EBV
give a recommendation for analgesia
alternate paracetamol and ibuprofen - both are anti-pyretic and analgesic
when should EBV be suspected
sore throat and malaise persist after ABX treatment, order WBC and Paul-Bunnell