Addiction Flashcards
What is drug abuse
Use of a drug in a manner not medically or socially approved
What is SUD
Substance Use Disorder
used instead of addiction
What is drug addiction
A disorder in pathologic decision making
Expression of compulsive destructive behavior despite extreme negative consequences.
Every drug is related to
enhance dopamine activity in uncles accumbens for pleasure.
What is the source of dopamine to the cortex
Substancia nigra
Substancia nigra is related to what disease
PD
Serotonin comes from
Rape
What D receptor is associated with pleasure
D2
What drugs cause DA release
Opioids Nicotine Marijuana Caffeine alcohol and sedative hypnotic
Caffeine blocks
Adenosine receptors
Alcohol and sedative hypnotics activate what what receptors
GABA
What drugs block transporter
Coccaine
ritalin
What do amphetamine drugs do
Release DA from vesicles and reverse transporter
What does the orbitofrontal central cortex do
Establishes priorities and motivation to assist PFC in decision making
What does the amygdala nucleus accumbent do
Impulsivity center, rapidly selects behavior based on dominance, rewards and perceived immediate emotional needs
