Adaptive Immunity Flashcards
has ability to differentiate between normal “self” cells and
“nonself”
Adaptive Immunity
distinguished from innate immunity by its specificity and
memory
Adaptive Immunity
What is the dual nature of adaptive immunity
Humoral immunity
Cell mediated immunity
refers to a component of the adapative immunty where B cells secrete antibodies, which circulate in the blood as a soluble protein
Humoral immunity
refers to the other component of the adaptive immunity which is mediated by the activated antigen-specific T cells
Cell mediated immunity is
Mediated by B cells
Humoral immunity
Mediated by T cells
Cell mediated immunity
Mediated by T cells, B cells, and macrophages
Humoral immunity
Acts on extracellular microbes and their toxins
Humoral immunity
Mediated by helpter T cells, Cytotoxic T cells, natural killer cells, and macrophages
Cell mediated
Part of antigent that triggers immune responses and react with antibodies
Epitope or Antigenic determinant
Either proteins or polysaccharides
Antigent
MW greather than or equal to 10,000 Da
Antigents
Low molecular weight compounds that are antigenic when attached to a carrier molecules; has no reactivity but no immunogenicity
Haptens
MHC
Major Histocompatibility Complex
Another name known of MHC or Major histocompatibility complex
HLA or Human Leukocyte antigent
Self antigen
MHC
Transmembrane proteins
MHC
Unique to an individual
MHC
Present in all body cells except RBCs
MHC
Help T cells to recognize that antigen is foreign, not self
MHC
Present in all body except red blood cells
MHC-I
Present in antigen-presenting cells (APCs)
MHC-II
Enumerate the process of Cell mediated immunity
Processing of Antigen
Activation of T cells
Elimination of Antigen