Adaptive Immunity Flashcards

1
Q

has ability to differentiate between normal “self” cells and
“nonself”

A

Adaptive Immunity

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2
Q

distinguished from innate immunity by its specificity and
memory

A

Adaptive Immunity

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3
Q

What is the dual nature of adaptive immunity

A

Humoral immunity
Cell mediated immunity

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4
Q

refers to a component of the adapative immunty where B cells secrete antibodies, which circulate in the blood as a soluble protein

A

Humoral immunity

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5
Q

refers to the other component of the adaptive immunity which is mediated by the activated antigen-specific T cells

A

Cell mediated immunity is

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6
Q

Mediated by B cells

A

Humoral immunity

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7
Q

Mediated by T cells

A

Cell mediated immunity

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8
Q

Mediated by T cells, B cells, and macrophages

A

Humoral immunity

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9
Q

Acts on extracellular microbes and their toxins

A

Humoral immunity

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10
Q

Mediated by helpter T cells, Cytotoxic T cells, natural killer cells, and macrophages

A

Cell mediated

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11
Q

Part of antigent that triggers immune responses and react with antibodies

A

Epitope or Antigenic determinant

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12
Q

Either proteins or polysaccharides

A

Antigent

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13
Q

MW greather than or equal to 10,000 Da

A

Antigents

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14
Q

Low molecular weight compounds that are antigenic when attached to a carrier molecules; has no reactivity but no immunogenicity

A

Haptens

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15
Q

MHC

A

Major Histocompatibility Complex

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16
Q

Another name known of MHC or Major histocompatibility complex

A

HLA or Human Leukocyte antigent

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17
Q

Self antigen

A

MHC

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18
Q

Transmembrane proteins

19
Q

Unique to an individual

20
Q

Present in all body cells except RBCs

21
Q

Help T cells to recognize that antigen is foreign, not self

22
Q

Present in all body except red blood cells

23
Q

Present in antigen-presenting cells (APCs)

24
Q

Enumerate the process of Cell mediated immunity

A

Processing of Antigen
Activation of T cells
Elimination of Antigen

25
What are the two types of antigen in processing of antigen
Exogenous antigents Endogenous antigens
26
During activation of T cells, what is activated?
Helper T cells Cytotoxic T cells
27
Present in fluids outside body cells
Exogenous antigent
28
example are bacteria and bacterial toxins, parasitic worms, inhaled pollen and dust and viruses outside the cells
Exogenous antigen
29
Processed by APCs
Exogenous antigens
30
Present inside body cellls
Endogenous antigents
31
viral proteins produced after a virus infects the cell, toxins produced from intracellular bacteria, or abnormal proteins synthesized by a cancerous cell
Endogenous antigents
32
Processed by infected host cells
endogenous antigens
33
What are the costimulation of activation of T cells
1st signal: antigen-MHC complexes 2nd signal: cytokines
34
A subset of the helper T cells
Regulatory T Cell
35
Carry an additional CD25 glycoprotein
Regulatory T cell
36
protect the fetus during pregnancy
Regulatory T cell
37
immune's system recognition of tumor antigents on cancer cells, and their destruction by cytotoxic T cells, macrophages and NK cells.
Immunological Surveillance
38
what is antibodies also known as?
Immunoglobulins (Igs)
39
450 AAs
2 heavy chains
40
220 AAs
2 light chains
41
same in Igs of the same class
Constant (C) regions
42
contains the antigen-binding site
Variable (V) regions
43