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Micropara > Adaptive Immunity > Flashcards

Adaptive Immunity Flashcards

1
Q

has ability to differentiate between normal “self” cells and
“nonself”

A

Adaptive Immunity

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2
Q

distinguished from innate immunity by its specificity and
memory

A

Adaptive Immunity

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3
Q

What is the dual nature of adaptive immunity

A

Humoral immunity
Cell mediated immunity

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4
Q

refers to a component of the adapative immunty where B cells secrete antibodies, which circulate in the blood as a soluble protein

A

Humoral immunity

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5
Q

refers to the other component of the adaptive immunity which is mediated by the activated antigen-specific T cells

A

Cell mediated immunity is

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6
Q

Mediated by B cells

A

Humoral immunity

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7
Q

Mediated by T cells

A

Cell mediated immunity

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8
Q

Mediated by T cells, B cells, and macrophages

A

Humoral immunity

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9
Q

Acts on extracellular microbes and their toxins

A

Humoral immunity

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10
Q

Mediated by helpter T cells, Cytotoxic T cells, natural killer cells, and macrophages

A

Cell mediated

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11
Q

Part of antigent that triggers immune responses and react with antibodies

A

Epitope or Antigenic determinant

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12
Q

Either proteins or polysaccharides

A

Antigent

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13
Q

MW greather than or equal to 10,000 Da

A

Antigents

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14
Q

Low molecular weight compounds that are antigenic when attached to a carrier molecules; has no reactivity but no immunogenicity

A

Haptens

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15
Q

MHC

A

Major Histocompatibility Complex

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16
Q

Another name known of MHC or Major histocompatibility complex

A

HLA or Human Leukocyte antigent

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17
Q

Self antigen

A

MHC

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18
Q

Transmembrane proteins

19
Q

Unique to an individual

20
Q

Present in all body cells except RBCs

21
Q

Help T cells to recognize that antigen is foreign, not self

22
Q

Present in all body except red blood cells

23
Q

Present in antigen-presenting cells (APCs)

24
Q

Enumerate the process of Cell mediated immunity

A

Processing of Antigen
Activation of T cells
Elimination of Antigen

25
Q

What are the two types of antigen in processing of antigen

A

Exogenous antigents
Endogenous antigens

26
Q

During activation of T cells, what is activated?

A

Helper T cells
Cytotoxic T cells

27
Q

Present in fluids outside body cells

A

Exogenous antigent

28
Q

example are bacteria and bacterial toxins, parasitic worms, inhaled pollen and dust and viruses outside the cells

A

Exogenous antigen

29
Q

Processed by APCs

A

Exogenous antigens

30
Q

Present inside body cellls

A

Endogenous antigents

31
Q

viral proteins produced after a virus infects the cell, toxins produced from intracellular bacteria, or abnormal proteins
synthesized by a cancerous cell

A

Endogenous antigents

32
Q

Processed by infected host cells

A

endogenous antigens

33
Q

What are the costimulation of activation of T cells

A

1st signal: antigen-MHC complexes
2nd signal: cytokines

34
Q

A subset of the helper T cells

A

Regulatory T Cell

35
Q

Carry an additional CD25 glycoprotein

A

Regulatory T cell

36
Q

protect the fetus during pregnancy

A

Regulatory T cell

37
Q

immune’s system recognition of tumor antigents on cancer cells, and their destruction by cytotoxic T cells, macrophages and NK cells.

A

Immunological Surveillance

38
Q

what is antibodies also known as?

A

Immunoglobulins (Igs)

39
Q

450 AAs

A

2 heavy chains

40
Q

220 AAs

A

2 light chains

41
Q

same in Igs of the same class

A

Constant (C) regions

42
Q

contains the antigen-binding site

A

Variable (V) regions

Micropara (10 decks)

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