1 - Introduction to Microbiology Flashcards
the scientific study of microorganisms
Microbiology
minute living things that individually are usually
too small to be seen with the unaided eye
Microogranisms
Enumerate some microorganisms
Bacteria
Fungi
Protozoa
Algae
Viruses
aka microbiota
Microbiome
it is microbes that live stably in and on the human body
Microbiome
indefinitely colonize the body
normal microbiota
transiently colonize the body
transient microbiota
Enumerate some parts of a prokaryotic cell
Glycocaly
Cell Appendages
Cell Wall
Plasma Membrane
Cytoplasm
Ribosomes
Inclusion
Nucleoid
Endospores
Enumerate parts of Cell Appendages
Flagella
Axial Filaments
Fimbriae
Pili
aka Sugar Coat
Glycocalyx
a viscous (sticky), gelatinous polymer that is external to the cellwall
Glycocalyx
Composed of polysachharide, polypeptide, or bot
Glycocalyx
made inside the ell and secreted to the cell surface
Glycocalyx
What are the 2 types of Glycocalyx
Capsule
Slime Layer
Contributes to bacterial virulence
Capsule
Protects pathogenic bacteria from phagocytosis
Capsule
Long filamentous appendages that propel bacteria
Flagella
Movement of bacterium toward or away from a particular stiumlus
Taxis
What are some types of taxis
Chemotaxis
Phototaxis
aka endoflagella
Axial Filaments
bundles of fibrils that spiral around the cell
Axial filaments
structure for motility in spirochetes
Axial Filaments
arise and anchored at the ends of the cell beneath an outer sheath
Axial Filament
similar structure to flagella
Axial Filaments
Hairlike Appendages that are shorter, straigter, and thinner than flagella
Fimbriae and Pili
consist of a protein called pilin arranged helically around a central core
Fimbriae and Pili
Present in many g(-) bacteria
Fimbriae and Pili
a few to serveralo hundred per cell
Fimbriae
adhere to surfaces
Fimbriae
longer and fewer than fimbriae (1-2/cell)
Pili
for motility and DNA transfer (e.g. sex pili in conjugation)
Pili
Complex, semi rigid structure
Cell Wall
Enumerate the functions of Cell Wall
- prevents bacterial cell rupture
• maintain shape of bacterium
• point of anchorage for flagella
present in all bacteria, except Mycoplasma and Ureaplasma
cell wall
contributes to the ability to cause disease, the site of action of some antibiotics, differentiates major types of bacteria based on composition
Cell Wall
what is peptidoglycan
aka murein
composed of peptidoglycan (aka
murein) alone or in combination with
other substances
Cell Wall
Repeating Dissacharides
N-acetylglucosamine (NAG) + N-acetylmuramic acid (NAM)
NAG
N-acetylglucosamine
NAM
N-acetylmuramic acid
many layers of peptidoglycan, forming a thick, rigid structure
Gram-Positive Cell Wall
one or very few layers of peptidoglycan and an outer membrane
Gram-Negative Cell Wall
Major permeability barrier for Gram-negative bacteria
Gram-Negative Cell Wall:
Outer Membrane
Lipids and carbohydrates
Lipopolysaccharide (LPS)
released when g(-) bacteria die; causes fever,
shock, blood clotting, dilation of blood vessels)
Lipid A (Endotoxin)
structural function
Core polysachharide
Function as antigen
O Polysaccharide
It is also present in Listeria monocygenes (a Gram-Positive bacteria) but does not function as endotoxin
O-polysaccharide
between inner membrane and outer membrane
Periplasmic Space
present in Mycobacterium and Nocardia
Acid-Fast Cell Wall
contains high concentrations (60%) of a hydrophobic waxy lipid(mycolic acid)
Acid-Fast Cell Wall
Mycobacterium and Nocardia
Acid-Fast Cell Wall
inside the cell wall and encloses the cytoplasm
Plasma Membrane
consists mainly of phospholipids, proteins, glycoproteins, glycolipids
Plasma Membrane
lacks sterols, except Mycoplasma and Ureaplasma
Plasma Membrane
What is the structure of plasma membrane?
Fluid Mosaic Model