actual exam 3 Flashcards

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1
Q

What epigenetic modification increases the rate of gene expression?

A

-Treating the histones w/ histone acetyltransferase

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2
Q

What syndrome has paternally imprinted genes?

A

-Angelman syndrome

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3
Q

What are 2 important characteristics of Epigenetics?

A
  • They allow different cell types to have different patterns of gene expression
  • And they’re hertiable
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4
Q

When are genes silenced?

A

-When DNA is methylated at cytosines followed by guanines

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5
Q

What are 3 characteristics about chordates?

A
  • A notochord is present during development
  • Pharyngeal slits are present during some of the embryotic development
  • A single hollow nerve chord is present during some stage of embyronic development
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6
Q

Where do cleavage divisions occurs in the blastocyst?

A

-They occur in the oviduct and uterus

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7
Q

What is the potency of germ layers that are produced in their home of the Gastrula?

A

-They are pluripotent

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8
Q

What are 2 important characteristics about Morphogens?

A
  • They are diffusable

- They stimulate developmental events depending of concentration

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9
Q

What is Congenital Zika Virus associated with?

A

-A pregnant mother exposed to the zika virus through the bite of an aedes aegypti

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10
Q

What does Congenital Zika Virus cause?

A
  • Macular damage

- Microcephaly

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11
Q

When are babies most likely to suffer the greatest developmental damage due to Congenital Zika Virus?

A
  • When they are exposed to the virus within the first trimester
  • When they have CNS neurons w/ Zika infections
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12
Q

Where are mammalian embyronic stem cells obtained from?

A

-The inner cell mass

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13
Q

What is a sensory neuron the component of?

A

-The PNS

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14
Q

What it the myelin like of a sensory neuron?

A

-It’s made up of schwann cells

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15
Q

What is the relationship between axon diameter and conduction speed?

A

-It’s a direct relationship; so as diameter increase, conduction speed increases

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16
Q

Which ion channels change shape in response to a threshold voltage being reached?

A
  • Potassium
  • Calcium
  • Sodium
17
Q

What happens to Acetylcholine at the neural muscular junction?

A

-It is released as a result of calcium ions entering the axon terminal

18
Q

What occurs when the skeletal muscle is at rest?

A
  • Tropomyosin covers myosin binding sites

- Voltage-gated calcium channels in the sarcoplasmic reticulum are closed

19
Q

What do the muscle cells form in skeletal muscles?

A

-The muscle cells make up the Z-line

20
Q

What must occur for the skeletal muscle to produce the sliding filament action?

A

-Cross bridges must form due to the myosin binding sites being exposed

21
Q

What role does Tropomyosin play on actin?

A

-It covers the binding sites on actin

22
Q

What kind of channels do T-tubules have in their membrane?

A

-Voltage-gated ion channels

23
Q

What is the purpose of T-Tubules?

A

-They propogate action potentials through a myofiber

24
Q

What does the DNA methlyation inhibitor RG108 show promise of treating?

A

-Cocaine addiction