ACTUAL EXAM 2 Flashcards
Where does the redundancy of the genetic code reside in?
-The 3rd base of the codon
What are 2 key characteristics of the Sigma Factor of prokaryotes?
- Part of the Haloenzyme
- Necessary for promoter recognition
What is Single-Nucleotide Polymorphism?
-A single base difference in DNA among individuals in a population & have no effect on phenotype
What is the role of Terminator Sequences?
-Causes the dissociation between RNA polymerase and DNA
Approx what percent of the human genome is made of protein-coding genes?
2%
What is Aminoacyl tRNA synthase used for?
-To charge initiator tRNA
What 3 things are true about Autism Speaks & Autism Speaks Genome Project?
- Chromosomes are associated w/ suceptibility to the disorder may have copy number variants are certain genetic loci
- Males are affected 4x more than femals
- New mutations are associated w/ disorder increase w/ paternal age
What is Ubiquitination?
-Post-translational modifications that targets a protein for destruction in proteosome
What is true about Protein synthesis?
-The ribsosome is translocated along the mRNA so new charged tRNA may enter A site
What is the role of RNA pol I?
-It is specific for transcription of rRNA and would be found in the nucleus
What happens during RNA processing?
-Introns are removed from the RNA in prokaryotes and eukaryotes
What are the Beta-Pleated sheets formed by?
-The hydrogen bond between the backbone of different amino acids
What are the 3 characteristics of genetic loci that assort independently
- They aren’t linked
- They may be located on seperate chromosomes or on the same chromosome
- crossing over may occur between the 2 loci
What are the components of Spiceosomes?
-Small nuclear RNA= recognizes intronic sequences
What can a single gene be used for?
-To produce a variety of transcripts that differ in sequence
