Acquired Alopecia Flashcards

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0
Q

What is the actively fully growing stage?

A

Anagen

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1
Q

Find flow chart on learn

A
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2
Q

What occours at catagen?

A

Follicular epithelium retracts upwards, dermal papilla starts to migrate upwards

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3
Q

What happens during telogen?

A

Hair anchored, dermal papilla close to surface and inactivve

- nothing much happening

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4
Q

which hormones regulate hairgrowth? What else affects hairgrowth?

A
  • thyroid
  • GCs
  • sex hormones
  • IGF-1
  • PRL, melatonin
    > nutrition
    > regional differences
    > local differences (hormonesmediators, growth fctors, cytokines)
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5
Q

Define alopecia

A
  • baldness or loss of hair
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6
Q

Define hypotrichosis

A

Mild alopecia or congenital alopecia

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7
Q

Define the problem of alopecia

A
1* alopecia  
- damage/loss  follicle (eg. burns) 
- cell cycle arrest (eg. chemo)
- dysfunctional follicle
2* trauma (self trauma or rubbing tack etc.)
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8
Q

Refine the problem of alopecia

A
  • inflammatory
    > inflam may be targetted at hair follicle or epidermal spread to/accidentally affecting follicle (bystander eg. leishmaniosis)
    > hair follicle (bacterial, dermnatophytes, demodex causes)
  • non-inflammatory
    > endocrine (other signs should be present, hairs arrest in telogen phase: telogenisation)
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9
Q

What is alopecia X?

A
  • unclear aetoiology
  • cosmetic problem only
  • local endocrine problem? no systemic problems found
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10
Q

Rarer causes of alopecia?

A

> miscellanesous hair cycle/growth problems
- colour linked alopcia in dilute breed (melanin clumping in hair shaft makes them weak and they break off)
- recurrent flank alopecia (symmetrical, hyperpigmentation, cosmetic problem, recurs annually then grows back, tx with sunscreen!)
- irish water spaniels breed for some areas long coat and some patches of short coat -> selecting for distorted hair follilces
- patterns baldness (miniaturisation of hari follicles)
other causes (rare)

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11
Q

Outline diagnostic approach to alopecia

A

> selfinflicted traumatic removal - work up as pruritis
inflammatory (demodex, staph, dermatophytosis)
non-inflam - r/o endocrine , histopathg

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12
Q

What syndrome do greyhounds and whippets get?

A
  • bald thigh syndrome
    > thyroid related?
  • normally low thyroid anyway
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13
Q

Non-inflammatory alopecia tx?

A
  • if not causing a problem do not treat!

- some people treat with a steroid hormone thing (look up)

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