Abx Classifications Flashcards

1
Q

Do PCNs cover MRSA

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the 1st generation cephalosporins that cover mostly gram + (staph and strep) not MRSA

A

cephalexin (Keflex)

cefazolin (Ancef)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

2nd gen cephalosporins are more gram - coverage and are used more for what

A

respiratory infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3rd gen cephalosporin examples? coverage?

A
  • ceftriaxone (Rocephin)
  • Ceftibuten (cedax)
  • cefoxatime (Claforan)
  • less gram pos, more gram neg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

___ is a 4th generation cephalosporin and has pseudomonal activity with good gram ____ coverage

A
  • cefepime (Maxipime)

- gram positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

which is the only cephalosporin to have MRSA coverage

A

ceftaroline (Teflaro)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Carbapenems are part of the _____ family and have gram ____ coverage

A
  • beta-lactam

- negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

_____ are watched carefully due to high risk of resistance

A

Carbapenems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ertapenem has ____ coverage but NO pseudomonas coverage

A

negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the beta-lactam inhibitors? which has pseudo coverage?

A
  • amoxicillin/clavulanic acid (Augmentin)
  • piperacillin/tazobactam (Zosyn) = Psuedo Cov.
  • ampicillin/sulbactam (Unasyn) (dog/cat bites)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

which bacteria do fluoroquinolones cover

A

gram - and gram +

cipro and levofloxacin have good pseudo coverage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the fluoroquinolones? which are good for resp?

A
  • ciprofloxacin
  • levofloxacin (resp)
  • moxifloxacin (resp)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do macrolides cover

A
  • atypical pna
  • pertussis
  • H. flu
  • some gram +
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are ex of macrolides

A
  • erythromycin
  • azithromycin
  • clarithromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what do sulfas cover? example?

A

gram - and MRSA

trimethoprim/sulfamethoxazole (Bactrim)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

lincosamide ex? what does it cover

A
  • clindamycin

- gram + and anaerobic (ABOVE diaphragm)

17
Q

glycopeptide ex? what does it cover

A

vancomycin

gram + and MRSA

18
Q

differentiate between vancomycin routes of administration

A
PO = for c. diff
IV = systemic
19
Q

tetracycline examples? what do they cover

A
  • doxycycline
  • minocycline
  • tetracycline

gram + and MRSA
skin and some respiratory

20
Q

Glycylcyline ex? what does it cover?

A

tigecyline (Tigacyl)

BROAD, w/ MRSA,
NO pseudo

21
Q

Oxazolidinones ex? what does it cover

A

-zolids

gram + and MRSA

22
Q

Lipopeptide ex? coverage?

A

daptomycin (Cubicin)

gram + and MRSA
no lung penetration

23
Q

Nitroimidazole ex? coverage?

A
  • metronidazole (Flagyl)
  • tinidazole (Tindamax)

anaerobic coverage BELOW diaphragm

24
Q

commons antifungals and typical coverage

A
  • fluconazole (Diflucan) – general yeast
  • miconazole (Monistat) – vag yeast
  • voriconazole (Vfend) – serious fungal infxn, molds