ABO Discrepancies Flashcards
1
Q
ABO Discrepancies
A
Strength of rxn: weak or missing (age, immunosuppressed)
Additional rxn: acquired B (forward), Rouleaux (multiple myeloma, reverse), cold antibody (reverse), autoantibody (both), dilution (plasma exchange, massive tx)
Abnormal rxn: mixed field (recent tx with group O, bone marrow transplant)
2
Q
Potent Cold Rxn Auto-Antibodies
A
Antibody coats patient RBC and agglutinates spontaneously
3
Q
Weakened Antigen Expression
A
Subgroupd of A or B
Some leukemia’s, Hodgkin’s disease
Excess soluble A and B blood group substances caused by carcinoma of the stomach/pancreas
Age, immunosuppressed
4
Q
Acquired B Antigen
A
Secondary to bowel obstruction or carcinoma of the bowel
