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Step 1 > AB's in different d/o's > Flashcards

AB's in different d/o's Flashcards

1
Q

Myasthenia gravis?

A

Anti-ACh receptor

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2
Q

Goodpasture syndrome?

A

Anti-BM

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3
Q

SLE shared w/ antiphospholipid syndrome? (2)

A

Anti-cardiolipin, lupus anticoagulant

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4
Q

CREST syndrome? (limited scleroderma)

A

Anti-centromere

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5
Q

Specific for SLE? (2)

A

Anti-dsDNA, anti-Smith (snRNPs)

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6
Q

T1DM?

A

Anti-glutamic acid decarboxylase (GAD-65)

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7
Q

Bullous pemphigoid?

A

Anti-hemidesmosome (BM)

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8
Q

Drug-induced lupus?

A

Anti-histone

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9
Q

Polymyositis, dermatomyositis?

A

Anti-Jo-1, anti-SRP, anti-Mi-2

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10
Q

Hashimoto thyroiditis?

A

Anti-microsomal, anti-thyroglobulin

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11
Q

Primary biliary cirrhosis?

A

Anti-mitochondrial

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12
Q

SLE, non-specific?

A

ANA

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13
Q

Pernicious anemia?

A

Anti-parietal cell

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14
Q

Primary membranous nephropathy?

A

Anti-phospholipase A2

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15
Q

Scleroderma (diffuse)?

A

Anti-DNA topoisomerase 1 (anti-Scl-70)

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16
Q

Autoimmune hepatitis type 1?

A

Anti-smooth muscle

17
Q

Sjogren syndrome?

A

Anti-SSA, anti-SSB (anti-Ro, anti-La)

18
Q

Graves disease?

A

Anti-TSH receptor

19
Q

Mixed CT disease?

A

Anti-U1 RNP (ribonucleoprotein)

20
Q

Lambert-Eaton syndrome?

A

Voltage-gated Ca2+ channel AB’s

21
Q

Celiac disease?

A

IgA anti-endomysial, IgA anti-tissue transglutaminase

22
Q

Another name for p-ANCA?

A

MPO-ANCA

23
Q

Another name for c-ANCA?

A

PR3-ANCA

24
Q

Diseases positive for p-ANCA?

A

Microscopic polyangiitis

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

25
Q

Disease positive for c-ANCA?

A

Granulomatosis with polyangiitis (Wegener)

26
Q

Rheumatoid arthritis?

A 
Rheumatoid factor (IgM AB that targets IgG Fc region)
Anti-CCP (more specific)
27
Q

Pemphigus vulgaris?

A

Anti-desmoglein (anti-desmosome, intercellular)

Step 1 (15 decks)

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