A4- Obesity

Question 1

What is obesity

Answer 1

Overweight and obesity are defined as abnormal or excessive
fat accumulation that presents a risk to health”
• A body mass index (BMI) > 25 kg/m2 is considered overweight,
and over 30 kg/m2 is obese.

The suggested BMI cut off now used to define obesity (≥30 kg/m2)
was developed from observational studies in Europe and the USA
of exclusively White populations and based on the association
between BMI and mortality.

Question 2

Obesity definition for Asian and Chinese

Answer 2

BMI cut-off of 27·5 kg/m2 be used for south Asian and Chinese
populations to trigger the implementation of lifestyle interventions.

Question 3

Causes of obesity

Answer 3

Energy balance: Energy intake equal to energy
expenditure

When this does not happen

Question 4

Adipose tissue can expand but has a finite capacity

TRUE OR FALSE

Answer 4

TRUE

Question 5

Excess energy that cannot be stored within subcutaneous
adipose tissue (SAT) so where is it stored?

Answer 5

Excess energy that cannot be stored within subcutaneous
adipose tissue (SAT) is stored elsewhere in visceral adipose
tissue (VAT) and in the organs

Question 6

Lipid excess can cause ______ _________ and _________ ____ ________ ______ in the absence of any other metabolic syndrome risk factors

Answer 6

Lipid excess can cause metabolic dysfunction and destruction of normal cells in the absence of any other metabolic syndrome risk factors

Question 7

Onesity increases the risk of?

Answer 7

Increased risk of type 2 diabetes (T2DM) and cardiovascular disease

Question 8

Complications of obesity

Answer 8

Question 9

What are Approved treatments for weight management?

Answer 9

Orlistat 60/120 mg TDS

Naltrexone 32 mg/ Bupropion 360 mg PR3

Liraglutide 3.0 mg daily

Semaglutide 2.4 mg Weekly

Setmelanotide 1-3mg od

Question 10

Liraglutide is a once-daily, human ____ __ analogue