A4- Benign & Malignant Skin Lesions (check video) Flashcards
1
Q
What is this called
A
Benign melanocytic naevi
- Congenital
- Acquired
- Junctional
- Compound
- Intra-dermal
2
Q
What is Melanoma
A
• Malignant neoplasm of melanocytes
3
Q
How common is melanoma?
A
• Fifth most common cancer in UK
4
Q
RF for melanoma?
A
- Fair skin
- Family history
- Previous melanoma
- Severe sunburn in childhood
- Multiple dysplastic naevi
- Large congenital naevi
- Immunosuppression
5
Q
What are the subtypes of melanoma?
A
- Superficial spreading
- Lentigo maligna (melanoma)
- Acral lentiginous (including subungual)
- Nodular
6
Q
Clinical features of melanoma?
A
ABCDE rule
Asymmetry
Border
Colour
Diameter
Elevation
7
Q
Management of melanoma?
A
- Excision biopsy
- Wide local excision
- Sentinel lymph node biopsy
- Surgical resection of metastases
- Immunotherapy
- Targeted therapy
- Palliative radiotherapy
8
Q
What are the two types of Keratinocyte cancer
A
- Basal cell carcinoma
- Squamous cell carcinoma
9
Q
COmpare
Basal cell carcinoma and Squamous cell carcinoma
A
Basal cell carcinoma
• Nodular
• Superficial
• Infiltrative (morphoeic)
• Pigmented
•Squamous cell carcinoma: Precursors: actinic keratosis and Bowen’s disease
10
Q
Risk factors of Keratinocyte cancer
A
- Chronic UV exposure
- Immunosuppression
- Fair skin type
- Genetic
- Sites of chronic inflammation, scars
11
Q
Tx for Keratinocyte cancer
A
- Excision
- Mohs micrographic surgery
- Radiotherapy
- For superficial BCC
- Curettage
- Photodynamic therapy
- Imiquimod
12
Q
is Squamous cell carcinoma usually curative
A
yes
13
Q
Actinic keratosis treatment
A
- Cryotherapy
- Curettage
- 5-fluorouracil cream (Efudix)
- Photodynamic therapy
- Imiquimod (Aldara, Zyclara)
- Diclofenac gel (Solaraze)
14
Q
Bowen’s disease
Tx
A
- Excise if suspicious
- Curettage
- Efudix
- Imiquimod
- Photodynamic therapy
15
Q
A
