9. Bacterial and Misc Enteric Diseases Flashcards
Etiology of Clostridial Enterotoxemia
Clostridium spiroforme
Predisposition to clostridial enterotoxemia is caused by:
Decreased in fiber Weaning Change from restricted feeding to ad libitum feeding Stress Coinfections Abx
C/S of clostridial enterotoxemia
Peracute death
Wt loss
Anorexia
Most commonly: Watery diarrhea with fetid odor
Gross pathology of clostridial enterotoxemia
Hemorrhagic necrotic typhlitis
Paintbrush hemorrhages over serosa
Histopathology of Clostridial enterotoxemia
Large, fluid-filled, edmatous cecum
Mucosal cell swelling, vacuolation
What kind of diet fed to weanlings predisposes them to Clostridial enterotoxemia?
Low fiber, high energy diet
Causes cecal hypomotility and more availability of simple carbohydrates (required for C. spiroforme proliferation)
Rabbit vulnerability to C. spiroforme - adults vs weanlings
Exposure alone causes dz in weanlings
Exposure alone is not enough to cause dz in weanlings
Tx for Clostridial enterotoxemia
IV fluids
Transfaunation
Probiotics
Abx
Prevention of Clostridial enterotoxemia
Feeding practices - don’t overfeed, avoid early weaning, change feed gradually, provide sufficient fiber
Colibacillosis etiology
E. coli
E. coli is normally found in the GI of rabbits - T or F?
F
What changes in cecal pH may cause colibacillosis?
Increases in cecal pH
5 types of pathogenic E. coli?
- Enteroinvasive
- Enterotoxic
- Enterohemorrhagic
- Enteroaggregative
- Enteropathogenic
Most common E. coli strain involved in rabbit enteric disease
Enteropathogenic
How does enteropathogenic E. coli cause disease?
Attach to mucosal surface, effacing the epithelium (flattening it)
This causes loss of microvilli, leading to diarrhea
Colibacillosis is seen most commonly in which age group/
4-6 week old weanlings