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Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents > 8. Viral Diseases of Rabbits > Flashcards

8. Viral Diseases of Rabbits Flashcards

1
Q

Adenovirus c/s

A

Enteritis in 6-8 week olds

Profuse diarrhea with low mortality

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2
Q

Rabbit parvovirus c/s

A

Asymptomatic

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3
Q

Etiology of Shope Papillomavirus

A

Cottontail Rabbit Papillomavirus

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4
Q

CRPV is in what family?

A

Papovaviridae

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5
Q

Transmission of CRPV

A

Insects, particularly rabbit ticks (Haemaphysalis leporis) and mosquitoes

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6
Q

Natural host of CRPV

A

Sylvilagus spp

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7
Q

CRPV c/s

A

Large, keratinized warts over neck, shoulder, abdomen

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8
Q

Why shouldn’t you worry about transmission of CRPV in a lab animal colony?

A

Oryctolagus do not shed as many virions as natural Sylvilagus host

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9
Q

Do CRPVs papillomas occur in the mouth in rabbits?

A

no

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10
Q

CRPVs Papillomas that do not regress turn into what?

A

SCC

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11
Q

25% of rabbits with SCC die due to what?

A

Metastasis

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12
Q

Which papillomavirus has Oryctolagus as natural host?

A

Rabbit Oral Papillomavirus

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13
Q

Where do rabbit oral papillomas occur?

A

Ventral tongue of 2-18 month old rabbits

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14
Q

Disease timeline of oral papillomas

A

Usually regress within a few weeks

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15
Q

Myxomavirus is what kind of virus?

A

Leporipoxvirus

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16
Q

Where is myxomatosis endemic?

A

Southwestern US

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17
Q

Natural reservoir of myxomatosis

A

Brush rabbit (Sylvilagus)

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18
Q

Myxoma virus transmission

A

Arthropod vector

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19
Q

Myxomavirus c/s in Oryctolagus

A

Severe disease with high mortality

20
Q

2 different strains of Myxomavirus

A

California strain - death within 1 week

South American strain - mean survival time of 11 days

21
Q

C/S of myxomavirus

A

Edema, mucopurulent discharge. South American strain causes hard, convex lumps over the body, head, ears

22
Q

Efficacy of Myxomavirus vaccine

A

Reduces mortality and c/s, not entirely protective

23
Q

Shope Fibroma Virus causes high mortality in which rabbits?

A

Neonates

24
Q

Why aren’t Oryctolagus a good source of infection for mosquitoes?

A

Low virus concentration in the skin

25
Q

C/S of shope fibroma virus

A

Firm, flattened tumors on legs, feet periorbital, perineal regions. Spontaneous regression occurs

26
Q

Shope fibrama vs Shope papilloma

A

Fibroma - flat, SQ, loose, rubbery.

Papilloma - heavily keratinized, irregular, projecting masses of skin

27
Q

Rabbit poxvirus C.S

A

Profuse nasal discharge -> macular papules over skin, spleen, resp tract, liver
Death in 7-10 days.

28
Q

Which poxvirus doesn’t have inclusion bodies?

A

Rabbit pox virus

29
Q

Leporid Herpesvirus 1 secondary name

A

Herpes sylvilagus

30
Q

Herpes sylvilagus C/S

A

No infection or dz in domesticated rabbits

31
Q

Herpes sylvilagus is a member of what family?

A

Gammaherpesvirus

32
Q

Leporid Herpesvirus 2 is a member of what family?

A

Gammaherpesvirus

33
Q

Leporid Herpesvirus 4 is a member of what family?

A

Alphaherpesvirus

34
Q

LHP-2 c/s

A

Asymptomatic

35
Q

LHP-4 c/s

A

High morbidity and mortality

Periocular swelling, purulent ocular d/c, hemorrhagic dermatitis, ataxia, torticollis, CNS signs

36
Q

Rabbits are a model for what herpesvirus?

A

HHV-1

37
Q

HHV-1 C/S in rabbits

A

CNS signs

38
Q

4 distinct species of Rabbit Calicivirus

A

Rabbit hemorrhagic disease virus
European brown hare syndrome virus
Rabbit calicivirus
Michigan rabbit calicivirus

39
Q

Calicivirus c/s

A

Very high morbidity, 100% mortality

40
Q

Major cause of death from calicivirus

A

DIC with deep vein thrombosis

41
Q

What may be the only lesion found with calicivirus?

A

Pale liver with periportal necrosis

42
Q

Calicivirus should be reported to whom?

A

State vet and USDA

43
Q

Rabbit Enteric Coronavirus clinical course

A

Death within 24 hours of c/s

Cardiomyopathy and pleural effusion also possible

44
Q

Rotavirus is within which family?

A

Reovirus

45
Q

When does rotavirus usually occur?

A

When maternal Abs wear off during weaning

46
Q

C/S of rotavirus

A

In neonates: Severe dz and death
>2weeks: few to no c/s
Diarrhea

Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents (18 decks)

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