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Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents > 16. Viral, Chlamydial, and Fungal Diseases of GPs and Hamsters > Flashcards

16. Viral, Chlamydial, and Fungal Diseases of GPs and Hamsters Flashcards

1
Q

C/S of GPAdV (GP Adenovirus)

A

Subclinical infection, symptomatic when stressed

Pneumonia, sudden death

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2
Q

Pathology of GPAdV

A

Lung chnages - consolidation of lungs, necrotizing bronchiolitis, basophilic intranuclear inclusions

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3
Q

Prevention of GPAdV

A

Rederivation

Obtain GPs from stocks without history of GPAdV

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4
Q

Family of Caviid Herpes Virus 2 (GP Cytomegalovirus)

A

Herpesviridae

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5
Q

Subfamily of Caviid Herpes Virus 2 (GP Cytomegalovirus)

A

Betaherpesvirinae

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6
Q

C/S of GP Cytomegalovirus

A 
Commonly subclinical
Conjunctivitis
Lymphadenopathy
Latent, persistent infection in salivary gland
Abortions, stillbirths
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7
Q

Histo lesions of GP Cytomegalovirus

A

Eosinophilic intranuclear inclusions in epithelium of salivary glands

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8
Q

Prevention of GP Cytomegalovirus

A

Select stock known to be free of the virus

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9
Q

Family of GP AdV, Genus

A

Family: Adenovirus
Genus: Mastadenovirus

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10
Q

Caviid herpesvirus 1 c/s (Hsiung or Kapow virus, GP herpes-like virus)

A

Subclinical, occasional fetal wasting

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11
Q

Caviid herpesvirus 3 c/s (Guinea Pig X virus)

A

Unknown. Exp infection can result in hepatic necrosis

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12
Q

Equid herpes virus 1 subfamily

A

Alphaherpesvirinae

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13
Q

Equid herpes virus 1 genus

A

Varicellovirus

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14
Q

Equid herpes virus 1 subfamily C/S in GP

A

Neurologic (ataxia and paralysis), abortion/stillbirths

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15
Q

LCMV family, genus

A

Family: Arenaviridae, Genus:Arenavirus

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16
Q

Transmission of LCMV

A

Aerosol - insects, fomites, contaminated food/bedding

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17
Q

C/S of LCMV in GPs

A

Usually none

Meningitis and hind limb paralysis have been observed

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18
Q

Prevention and control of LCMV

A

Eliminate wild mice, parasites

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19
Q

Corona-like infection C/S in GP

A

Anorexia, diarrhea, low morbidity/mortality

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20
Q

Pathology of Corona-like infection in GP

A

Mucus throughout SI, blunting of villi

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21
Q

Paramyxoviridae in GPs (5)

A
  1. Human parainfluenza virus type 3
  2. Caviid parainfluenza virus 3
  3. Sendai virus
  4. Simian virus 5
  5. Murine pneumonia virus

All have no C/S

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22
Q

Human parainfluenza virus type 3 can sometimes cause what pahtology?

A

Interstitial pneumonia

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23
Q

Cavian Leukemia family

A

Retroviridae, Leukovirus

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24
Q

C/S of Cavian Leukemia

A

Ruffled hair, pale MM, lethargy, lymphadenopathy, 2* infections

25
Q

Theiler’s murine encephalomyelitis virus family

A

Picornavirus

26
Q

Theiler’s murine encephalomyelitis virus transmission in GP

A

Fecal oral

27
Q

Theiler’s murine encephalomyelitis virus C/S in GP

A

Weight loss, paralysis

28
Q

Etiology of GP chlamydial disease

A

Chlamydia caviae

29
Q

Chlamydia caviae transmission

A

Ocular and nasal secretions

30
Q

Chlamydia caviae C/S

A 
Commonly subclinical
Conjunctivitis with serous/purulent d/c, chemosis, keratitis, photophobia
Rhinitis
Genital tract infections
Bronchopneumonia
31
Q

Dx of Chlamydia caviae

A

Conjunctival scrapings

32
Q

Chlamydia caviae prevention

A

Self-limiting. Has zoonotic potential

33
Q

Etiology of GP dermatophytosis

A

Trichophyton mentagrophytes. Rarely Microsporum canis

34
Q

C/S of GP dermatophytosis

A

Asymptomatic

Patchy alopecia, crusting, scaling

35
Q

Dx of GP dermatophytosis

A

PAS, silver stain (GMS)

Culture on Sabouraud’s agar

36
Q

Tx of GP dermatophytosis

A

Miconazole (topical), fluconazole (systemic)

37
Q

4 other misc GP fungal diseases

A
  1. Histoplasma capsulatum (emaciation, hindlimb lameness, conjunctivitis)
  2. Aspergillosis
  3. Cryptococcus neoformans
  4. Candida albicans
38
Q

Hamster Polyomavirus causes which disease?

A

Transmissible Lymphoma

39
Q

Transmission of Hamster Polyomavirus

40
Q

C/S of hamster poloymavirus

A

Subclinical
Multicentric lymphoma
Trichoepitheliomas on face, feet, neck, back, flanks

41
Q

Pathology of hamster poloymavirus

A

Lymphomas most commonly in intestines, mesentery, liver

42
Q

Dx of hamster polyomavirus

A

Observation of trichoepitheliomas

43
Q

Tx of hamster polyomavirus

A

Cull colony, decontaminate environment

44
Q

Hamster parvovirus c/s

A

Subclinical
Neonates and weanlings: runted with incisor abnormalities, domed cranium, potbellies
Diarrhea, ataxia, mortality

45
Q

Hamster parvovirus transmission

A

ingestion or inhalation

46
Q

What kind of adenovirus naturally infects hamsters?

A

MAdv-1 and MAdv-2

47
Q

Cricetid Herpesvirus (CrHV-1) C/S

A

Clinically silent, can cause SDAV in pet Cricetulus griseus

48
Q

Transmission of Sendai virus in hamsters

A

Direct contact with infected rodents or fomites

49
Q

Sendai virus C/S in hamsters

A

Subclinical
Death in suckling hamsters
Death with pulmonary lesions in Chinese hamsters

50
Q

Pathology of Sendai virus

A

Consolidation of lung lobes

51
Q

Prevention of Sendai virus

A

House hamsters in rooms separate from other rodents

52
Q

LCMV in hamsters

A

Natural reservoir is mice, but hamsters are a highly susceptible secondary reservoir

53
Q

LCMV transmission in hamsters

A

Verticla and horizontal - shedding occurs in urine, saliva, feces, milk, semen

54
Q

LCMV C/S in hamsters

A

Acute: No C/S
Chronic: Progressive wasting - hunched, weight loss, blepharitis

55
Q

Pathology of LCMV in hamsters

A

Lymphocytic infiltration of visceral organs, vasculitis, glomerulitis, influenza-like symptoms, subclinical

56
Q

Prevention and control of LCMV in hamsters

A

Purchase LCMV-negative hamsters

Pest control

57
Q

Hamster dermatophyte

A

Trichophyton mentagrophytes (Djungarian hamsters)

58
Q

Tx of hamster dermatophyte

A

Not effective, can try griseofulvin or topicals

Yale Residency - Rabbits, Guinea Pigs, Misc. Rodents (18 decks)

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