9/30/12 Flashcards
What is seen in the clinnical presentation of pemphigus vulgaris that is not seen in bullous pemphigoid?
mucosal involvement and bullae are flaccid and expand or erupt w/ traction
What disease is dermatitis herpeteformis associated with?
Celiac sprue!
What sedative drug may cause priapism?
Trazodone
What type of Ig would you find w/in dermatitis herpeteformis lesions?
IgA
Fever, dull abdominal pain, and watery diarrhea turned bloody (or constipation). Hepatosplenomegaly, and ROSE-COLORED SPOTS in the periumbilical area. Dx?
Typhoid fever - Salmonella typhi or S. paratyphi. (Salmon-colored spots –> Salmonella!)
Through which cells does Shigella enter the interstinal mucosa?
antigen-sampling M-cells (Peyer’s patches)
Why do patients w/ typhoid have hepatosplenomegaly?
MΦs which have phagocytosed the Salmonella carry them there\, as well as the bone marrow.
What bacteria did Typhoid Mary carry?
S. typhi, of course!
What causes death in typhoid?
intestinal hemorrhage and peritonitis/sepsis
In what case would the end-systolic volume increase while the afterload remains the same?
Ventricular dysfunction
How can a blood transfusion kill a person w/ selective IgA deficiency?
anti-IgA IgG can cause aan anaphylactic rxn
C1 complement component deficiency is associated w/ development of what disease?
SLE
