8B) Antenatal Care - Other Flashcards
How many appointments should an uncomplicated primip receive?
10
How many appointments should an uncomplicated multiple receive?
7
When should dating scan be done?
10-13+6
How much vitamin A is toxic?
> 700 micrograms
Food with lots of vitamin A
Liver
How much vitamin D in standard pregnancy?
10 micrograms (equivalent to 400 units) (found in pregnacare/healthy start)
What foods should be avoided to avoid listeriosis?
Only drinking pasteurised/UHT milk.
NO: soft cheeses, pate (even veggie), undercooked ready meals.
What foods should be avoided to avoid salmonella?
Raw/partially cooked eggs/mayonnaise
Raw/partially cooked meat.
When to screen for haemoglobinopathies and how?
Ideally by 10 weeks.
If prevalence sickle cell disease is high (>1.5 cases/100,000) then do lab screening.
If prevalence of sickle cell disease is low then do Family Origin Questionnaire. If high risk on FOQ or if MCH <27 then do lab screening.
When to do anomaly scan?
18-20+6
What infection screening is done at booking?
Asymptomatic bacteriuria
Hepatitis B
HIV
Syphilis
When to assess presentation by palpation?
From 36 weeks
When to auscultate FH?
Only if requested by mother
What percentage of deliveries in the UK were induced?
20%
What proportion of induced labours deliver without further intervention?
<2/3
15% Instrumental
22% EMCS
Preferred method of IOL
Vaginal PGE2 (tablets/gel one dose followed by second after 6h. pessary one dose over 24h)
When should post-dates IOL be offered?
Between 41+0 and 42+0
What monitoring should be offered to women who decline post-dates IOL?
Twice weekly CTG an ultrasound examination of maximum amniotic pool depth
When should women be offered sweeps?
Prior to any formal IOL.
40+41 weeks nullip. 41 weeks parous.
What monitoring should be offered during IOL?
Before IOL - assess Bishop score and do CTG.
Once contractions begin - CTG and if normal can then do I/A.
When to reassess Bishop score?
6h after tablet/gel, 24h after pessary
When is IOL classed as failure?
After 1 cycle
Risks of vitamin D deficiency in pregnancy
Classical:
- Low calcium and phosphate
- Secondary hyperparathyroidism
- Osteomalacia and Rickets
- Neonatal hypocalcemic tetany
Non-classical:
- Pre-eclampsia
- SGA
- GDM
- Fetal lung development
- Neonatal immune conditions e.g. asthma
- Increased risk primary CS
- Bacterial vaginosis
How much calcium does a developing fetes require?
30g
How much vitamin D is delivered after 30 mins in sunlight in white skin?
50,000 units
By how much does melanin diminish cholecalciferol production?
90%
Vitamin D supplementation in women at high risk of PET
800 units combined with calcium
Vitamin D supplementation in women at high risk of vitamin D deficiency
1000 units daily
Treatment of vitamin D deficiency
Cholecalcierol: 2800 units OD and 20,000 units OW for 4-6 weeks.
Ergocalciferol: 2800 units OD and 10,000 units BW for 4-6 weeks.
What are the key physiological changes that occur during air travel?
Altitude –> Reduced barometric pressure –> Reduced partial pressure O2 –> Reduced blood O2 saturation 10%
Humidity low 15% –> Increased insensible fluid losses.
Effect of air travel on pregnancy outcomes
No increase in adverse pregnancy outcomes
Change in fetal O2 pressures during air travel
None
Radiation risk from air travel/body scanners
Radiation not significant for passengers but can be for staff.
Total radiation from body scanners <2 min flying or 1h on ground.
When to advise against flying?
37 weeks in uncomplicated singletons and 32 weeks multiples.
Contraindications to air travel
- Hb <75
- Recent sickling crisis
- Recent haemorrhage
- Otitis media & sinusitis
- Serious cardiac or respiratory disease
- Recent GI surgery (where anastomoses could come under stress with gaseous expansion)
- Fracture (significant leg swelling can occur in flight)
What is the increased risk of VTE with prolonged air travel?
3 x increased
18% increase in risk for each 2 hour increase in travel time.
What is the incidence of VTE after flight?
1 in 4600 flights >4 hours
What percentage of non-pregnant people at high risk for VTE will develop DVT after prolonged air travel?
4-5%
What is the benefit of TEDs during air travel?
RR 0.1
How often to do in flight exercises?
Every 30 minutes
What is the change in steroid hormone physiology in pregnancy?
3 x increased cortisol levels (due to oestrogen stimulation of CBG and placental stimulation CRH) which peak in third trimester.
Postpartum cortisol levels remain normal but CRH and ACTH fall.
What is the placental enzyme which protects fetus from high doses of steroids?
11B-HSD2 (metabolises cortisol)
Duration of action of betamethasone/dexamethasone/prednisolone.
Beta and dex are long acting - 36-54h.
Prednisolone medium acting - 12-36h.
Which steroids are not inactivated by placental enzymes?
Betamethasone and dexamethasone.
Adverse effects of exogenous steroids
- May be increased risk orofacial clefts
- May be association with PTB
- May be association with reduced fetal weight, head and height
- GDM
- Trend towards poorer neurological outcomes.
What is the increase in risk of GDM for someone on LT steroids?
5-10 x increased
BF on steroids
Safe but avoid BF for 4h after dose of pred
Which drug involved in early pregnancy care can’t be used in women on long term steroids?
Mifepristone
What should happen if woman on LT steroids starts COCP?
Monitor for steroid toxicity
How many days background radiation is CXR equivalent to?
10 days
Background radiation dose to fetes during pregnancy
1mGY
What are stochastic effects of radiation?
Effects which can occur at any radiation level without known threshold e.g. increased risk of childhood malignancy.
What are deterministic effects of radiation?
Effects which are dependent on gestational age and dose used for diagnostic test.
Units of measurement for exposure
C/kg
Units of measurement for dose
Gy
Units of measurement for relative effective dose
Sv
Which types of imaging are very low dose (<0.1mGy)?
CXR Cervical XR Extremities Mammography CT Head and Neck
Which types of imaging are low to moderate dose (0.1-10mGy)?
Chest CT
Limited pelvimetry
Which types of imaging are high dose (10-50mGy)?
Abdominal/Pelvic CT
PET/CT
What can sonographers do to ensure safety of USS?
Keep mechanical index and thermal index as low as possible and limit exposure < 60 minutes.
Risks of gad contrast with MRI?
Nephrogenic systemic fibrosis, rheumatological/skin/inflammatory conditions. Increased risk SB and NND.
Which radioactive isotopes can be used?
Technetium-99m (for V/Q scans)
Don’t use radioactive iodine (don’t become pregnant in 6 months after)
Deterministic effects of radiation at different gestations
0-2 weeks: No effect at any dose
3-4 weeks: Possible increased miscarriage if >100Gy
5-10 weeks: Possible congenital anomaly at >100Gy, Fetal growth restriction (200-250)
11-17 weeks: Diminished IQ and Microcephaly
Gestational age >18 weeks - Effects not noted.
What is the reduction in mammography risk by lead shielding?
50%
What percentage of CTPA inconclusive v V/Q scan?
6% v 4%