8.2 brain disorders

Question 1

mechanism of alzheimer’s disease

Answer 1

deposition of amyloid protein, disruption of the neuronal cytoskeleton

Question 2

is there a basis for separate classification of mental and neurological disease?

Answer 2

no.

Question 3

most significant neurological diseases

Answer 3

alzheimer’s, epilepsy, parkinson’s, stroke

Question 4

mechanism of multiple sclerosis

Answer 4

destruction of myelin in the CNS

Question 5

D2 receptor antagonists are useful for treating what?

Answer 5

schizophrenia

Question 6

three types of epilepsy:

Answer 6

idiopathy (no known cause), secondary (caused by a known CNS injury or disorder), cryptogenic - no clear evidence of an etiological factor

Question 7

WHO’s 4 categories of nervous system disease

Answer 7

mental diseases, neurological disorders, learning and developmental difficulties, substance abuse disorder

Question 8

disorders of the nervous system affect what percentage of global burden of ill health?

Answer 8

10%

Question 9

alzheimer’s symptoms are commonly reduced by _____

Answer 9

dopamine antagonists

Question 10

a small change in an ion channel structure can lead to ______

Answer 10

epileptic seizures

Question 11

the two historical divisions of disorders

Answer 11

those that primarily affect the mind and those that can be associated with a known cause