8- Respiratory Tumors Flashcards

0
Q

Why are hemartomas glistening

A

They have cartilage

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1
Q

What are the common causes for coin lesions in the lung ?

A

Squamous cell Lung cancer/adenocarcinoma
Benign tumors
Granuloma(histolplasma and mycobacterium tuberculosis homis)

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2
Q

Scarring of lung from TB can lead to

A

Adenocarcinoma

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3
Q

Cigarette smoke is made of

A

Polycyclic hydrocarbons

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4
Q

Small cell carcinoma you treat with

A

Chemo

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5
Q

Most common sites bronchi genie carcinomas metastasize to?

A

Adrenal glands-mc
Liver
Brain
Bones

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6
Q

Three diseases that lead to cavitation due to necrosis-cystic cavity

A
Squamous cell car** second MC
2-TB* most common 
Lung abscess
Hodgkin's lymphoma 
Aspergillus tumogatus
Klebsiella
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7
Q

Things that cause lung abscess -caseous liquefactive necrosis

A

Staph aureus
Klebseilla pneumonia

Aspiration pneumonia -oropharngea

Bronchogenic carcinoma
Infective endocarditis-tricuspid

Mycobacterium tuberculosis
homis

Histoplasmacapsulatum

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8
Q

What hormones does sq cc secrete and what does it lead to

A

PTHrP

Hypercalcemia

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9
Q

What cancer makes keratin pearls contains what?

A

Squamous cell
Large polyclonal cells with keratinization
Bright orange red

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10
Q

Sq. CC originate from what cells and where in lungs

A

Paeduostratified ciliated columnar epithelium

Large bronchi-main stem

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11
Q

Is adeno carcinoma medially or peripherally located?

A

Peripherally

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12
Q

Where does bronchioalveolar carcinoma originate from ?

A

Small airways like terminal bronchioles , respiratory bronchioles , alveolar wall cells

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13
Q

What are Clara cells? And what cancer involves them

A

The nonciliated cells of the small airways

Bronchioalveolar carcinoma

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14
Q

How Do lungs look on xrays of bronchioalveolar carcinoma?

A

Considation similar to pneumonia

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15
Q

What is the pattern if spread of bronchioalveolar carcinoma

A

Lepidic growth pattern

16
Q

Bronchoalveolar on microscope

A

Picket hobnail appearance

17
Q

Where is small cell carcinoma derived from

A

Kultchisty neuro endocrine cell from neuro crest

18
Q

Is brochioveolar well differentiated or undifferentiated

A

Well differentiated

19
Q

How is Small cell carcinoma differentiated

A

Undifferentiated anaplastic highly malignant

20
Q

Small cell tumor is positive for what markers

A

S100
Neuron specific enolase
Bombesin, synoatophysin, neuro filaments

All from neural crest origin

21
Q

Small cell carcinoma obstruction leads to

A

atelactasis and bronchiectasis

22
Q

What lung cancer leads to superior vena cava syndrome

A

Small cell carcinoma

23
Q

What cancer leads to Horner syndrome

A

Squamous cell pancoast carcinoma

24
Q

Brochiocarcinoma spread to Adrenal gland results in what disease

A

Addison’s disease

25
Q

What cancer leads to hycoaguability syndromes

A

Adenocarcinoma

26
Q

What does hypercoaguability from adenocarcinoma lead to?

A

Migratory thrombophlebitis
Non bacterial thrombotic endocarditis

Disseminated intravascular coagulation

27
Q

Carcinoid of the lung originate from what area of lung and origin

A

Large bronchi and nuero endocrine origin

28
Q

Cannon ball appearance on X-ray usually come from where

A

Breast, kidney, chariocarcinoma, sarcoma

29
Q

Where in the lung are pancoast tumor usually located

A

Apex of lung

30
Q

What is found in the middle of keratin pearls as they get larger

A

Necrosis

31
Q

Where lung cancers metastasize from

A

Breast Kidney gall bladder

Colon, bone