8- Respiratory Tumors Flashcards
Why are hemartomas glistening
They have cartilage
What are the common causes for coin lesions in the lung ?
Squamous cell Lung cancer/adenocarcinoma
Benign tumors
Granuloma(histolplasma and mycobacterium tuberculosis homis)
Scarring of lung from TB can lead to
Adenocarcinoma
Cigarette smoke is made of
Polycyclic hydrocarbons
Small cell carcinoma you treat with
Chemo
Most common sites bronchi genie carcinomas metastasize to?
Adrenal glands-mc
Liver
Brain
Bones
Three diseases that lead to cavitation due to necrosis-cystic cavity
Squamous cell car** second MC 2-TB* most common Lung abscess Hodgkin's lymphoma Aspergillus tumogatus Klebsiella
Things that cause lung abscess -caseous liquefactive necrosis
Staph aureus
Klebseilla pneumonia
Aspiration pneumonia -oropharngea
Bronchogenic carcinoma
Infective endocarditis-tricuspid
Mycobacterium tuberculosis
homis
Histoplasmacapsulatum
What hormones does sq cc secrete and what does it lead to
PTHrP
Hypercalcemia
What cancer makes keratin pearls contains what?
Squamous cell
Large polyclonal cells with keratinization
Bright orange red
Sq. CC originate from what cells and where in lungs
Paeduostratified ciliated columnar epithelium
Large bronchi-main stem
Is adeno carcinoma medially or peripherally located?
Peripherally
Where does bronchioalveolar carcinoma originate from ?
Small airways like terminal bronchioles , respiratory bronchioles , alveolar wall cells
What are Clara cells? And what cancer involves them
The nonciliated cells of the small airways
Bronchioalveolar carcinoma
How Do lungs look on xrays of bronchioalveolar carcinoma?
Considation similar to pneumonia
What is the pattern if spread of bronchioalveolar carcinoma
Lepidic growth pattern
Bronchoalveolar on microscope
Picket hobnail appearance
Where is small cell carcinoma derived from
Kultchisty neuro endocrine cell from neuro crest
Is brochioveolar well differentiated or undifferentiated
Well differentiated
How is Small cell carcinoma differentiated
Undifferentiated anaplastic highly malignant
Small cell tumor is positive for what markers
S100
Neuron specific enolase
Bombesin, synoatophysin, neuro filaments
All from neural crest origin
Small cell carcinoma obstruction leads to
atelactasis and bronchiectasis
What lung cancer leads to superior vena cava syndrome
Small cell carcinoma
What cancer leads to Horner syndrome
Squamous cell pancoast carcinoma
Brochiocarcinoma spread to Adrenal gland results in what disease
Addison’s disease
What cancer leads to hycoaguability syndromes
Adenocarcinoma
What does hypercoaguability from adenocarcinoma lead to?
Migratory thrombophlebitis
Non bacterial thrombotic endocarditis
Disseminated intravascular coagulation
Carcinoid of the lung originate from what area of lung and origin
Large bronchi and nuero endocrine origin
Cannon ball appearance on X-ray usually come from where
Breast, kidney, chariocarcinoma, sarcoma
Where in the lung are pancoast tumor usually located
Apex of lung
What is found in the middle of keratin pearls as they get larger
Necrosis
Where lung cancers metastasize from
Breast Kidney gall bladder
Colon, bone
