15-endocrine Flashcards

0
Q

Suprasella extension

A

Tumor that grow out of sella turica

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1
Q

Sella turica is a concavity of what bone

A

Sphenoid bone

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2
Q

Where do pituitary develop from embryologically

A

Oral ectoderm - raphe pouch

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3
Q

Mcc of pituitary hyperfunction

A

Adenoma

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4
Q

Mc pituitary adenoma

A

Prolactinoma

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5
Q

Pituitary disorders with bitemporal hemonospia

A

Prolactinoma

Non functioning pituitary adenoma

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6
Q

Prolactin inhibits what hormone

A

GnRH

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7
Q

Treat meant for prolactinoma

A

Bromocriptine
Cabregoline
Quinagolide

Dopamine analogies

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8
Q

GH stimulates what

A

Gluconeogenesis
Amino acid uptake
IGF-1

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9
Q

Excessive growth hormone does what to your blood sugar levels

A

DM- too much glucose

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10
Q

Other name for IGF-1

A

Somatomedin C

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11
Q

Treatment for GH adenoma

A

Octreotide- somatostatin analog

GH receptor antagonist-pegvisomant

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12
Q

Nelson’s syndrome

A

Surgery removal of adrenal gland cause rapid growth pituitary adenoma -more ACTH more MSH = hyper pigmentation

Iatrogenic cushings

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13
Q

Basophilic cells of pituitary

A

ACTH
TSH
FSH
LH

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14
Q

Pink pituitary cells

A

GH

PRL

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15
Q

Ca blocks

A

PTH

16
Q

What hormone stimulates prolactin release

A

TRH

17
Q

Stalk transaction damages what

A

Dopaminergic neurons

18
Q

NPA order if succession of hormone deficiency

A
Gonadotropins
GH
Tsh
ACTH
Prolactin
19
Q

Pituitary undergoes what kind of necrosis

A

Coagulation necrosis

20
Q

What hormone deficiencies do you treat first

A

ACTH and then TSH - with corticosteroids or leads to adrenal crisis

21
Q

Hormones that inhibit prolactin

A

Estrogen
Progesterone
Dopamine