15-endocrine Flashcards
Suprasella extension
Tumor that grow out of sella turica
Sella turica is a concavity of what bone
Sphenoid bone
Where do pituitary develop from embryologically
Oral ectoderm - raphe pouch
Mcc of pituitary hyperfunction
Adenoma
Mc pituitary adenoma
Prolactinoma
Pituitary disorders with bitemporal hemonospia
Prolactinoma
Non functioning pituitary adenoma
Prolactin inhibits what hormone
GnRH
Treat meant for prolactinoma
Bromocriptine
Cabregoline
Quinagolide
Dopamine analogies
GH stimulates what
Gluconeogenesis
Amino acid uptake
IGF-1
Excessive growth hormone does what to your blood sugar levels
DM- too much glucose
Other name for IGF-1
Somatomedin C
Treatment for GH adenoma
Octreotide- somatostatin analog
GH receptor antagonist-pegvisomant
Nelson’s syndrome
Surgery removal of adrenal gland cause rapid growth pituitary adenoma -more ACTH more MSH = hyper pigmentation
Iatrogenic cushings
Basophilic cells of pituitary
ACTH
TSH
FSH
LH
Pink pituitary cells
GH
PRL
Ca blocks
PTH
What hormone stimulates prolactin release
TRH
Stalk transaction damages what
Dopaminergic neurons
NPA order if succession of hormone deficiency
Gonadotropins GH Tsh ACTH Prolactin
Pituitary undergoes what kind of necrosis
Coagulation necrosis
What hormone deficiencies do you treat first
ACTH and then TSH - with corticosteroids or leads to adrenal crisis
Hormones that inhibit prolactin
Estrogen
Progesterone
Dopamine