19-thyroditis

Question 0

Hashimoto’s thyroiditis histology ?

Answer 0

Lymphoid follicles composed of aggregated lymphoid cells with germinal centers and B cells

Background thyroid cells

Pale areas -fibrosis

Question 1

Most common form of thyroiditis

Answer 1

Hashimotos

Question 2

Hashimotos gene association is ?

Answer 2

HLA DR-5

Question 3

The cells that stimulate antibody production in Hashimotos

Answer 3

Cd4t cells

Question 4

The thyroid in hashimotos is destroyed by what cells ?

Answer 4

Cd8 T cells

Question 5

Hasitoxicosis

Answer 5

Initial hyperthyroidism of Hashimotos

Initial thyrotoxicosis

Question 6

What is the most common cause of painful thyroid gland ?

Answer 6

Subacute Granulomatous thyroiditis - de quervains thyroiditis

Question 7

Histology of de quervains thyroiditis ?

Answer 7

Granulomatous inflammation with mutlinulcleated giant cells

macrophages

Question 8

Subacute Granulomatous thyroiditis uptake scan ** unlike other hyperthyroidism

Answer 8

Reduced because inflammation involves destruction of thyroid follicles

Question 9

What virus can cause de quervains disease?

Answer 9

Coxsakie a

Question 10

What usually causes Acute thyroiditis ?

Answer 10

Staph aureus

Question 11

The thyroid of acute thyroiditis presents with

Answer 11

Cervical lymphadenopathy

Question 12

What is the most common form of thyroid enlargement in the United States

Answer 12

Sporadic goiter

Question 13

Micro of multinodular goiter

Answer 13

Colloid rich irregular enlarged follicles lined by flat follicular cells

Question 14

Gross anatomy of mutlinodular goiter

Answer 14

Irregular nodules with cyst formation and areas of hemorrhage and fibrosis

Question 15

Ab in Hashimotos

Answer 15

Antithyroglobulin
Antimicrosomal-thyroperoxodase ab
Anti thyroid peroxidase
TSH receptor inhibitor

Question 16

Hashimotos has an increased incidence for what cancer

Answer 16

Mantle cell lymphoma - from shrinkage suddenly enlarges . This is when it’s cancer

Question 17

What is the analog of t4

Answer 17

L-tyroxine

Question 18

Course of subacute granulomTous thyroiditis - de quervains thyroiditis

Answer 18

Euthyroid- transient hyperthyrodism - euthyroid

Question 19

What is the consistency of the thyroid in reidels thyroiditis

Answer 19

Irregular hard woody consistency that adheres to surrounding structures of neck

Fibrosis

Question 20

Who does reidels affects

Answer 20

People in their 30-40

Question 21

Who gets subacute lymphocytic thyroiditis

Answer 21

3-6 month postpartum

Question 22

In subacute Granulomatous thyroiditis painful or painless

Answer 22

Painful

Question 23

Is subacute lymphocytic thyroiditis painful or painless

Answer 23

Painless

Question 24

Goiter thyroid levels

Answer 24

Normal t3-t4

Increased TSH

Question 25

What causes a simple colloid goiter to turn to a nodular goiter

Answer 25

Degenerative changes that evoke hemorrhage fibrosis and calcification

Question 26

What is a dyshormogenic goiter

Answer 26

Goiter that develops due to deficiency of enzyme involved in synthesis of thyroid hormones

Question 27

What are the characteristics of a multinodular goiter

Answer 27

Multilobed assymetrical enlarged follicles lined by flat follicular cells

Question 28

A simple goiter is

Answer 28

Diffused nontoxic

Question 29

Mutlinodular goiter can become

Plummers disease is what ?

Answer 29

Toxic nodular goiter called plummers disease

Which is when one or more nodules become TSH independent and lead to increase in t3 and t4 releasing be and causing thryotoxicosis- hot nodules

Question 30

How are most people with mutlinodular goiters

Answer 30

Euthyroid