8. Intro to metabolism

Question 1

CATABOLISM

Answer 1

break down macromolecules energy into biologically useful energy

Question 2

ANABOLISM

Answer 2

Those that require the input of energy to form complex molecules from smaller ones

Question 3

Negative feedback

Answer 3

product from another process downstream of that reaction inhibits the process by inhibiting the enzymes activity

Question 4

Positive Feedforward

Answer 4

raising levels of a substrate increases the activity of an enzyme which in turn causes the precursor to be used up

Question 5

Positive Feedback

Answer 5

the effect caused by an action stimulates the action even more

Question 6

Allosteric control

Answer 6

binding of an effector molecule at a site other than the active site

Question 7

Specificity

Answer 7

high = binding only one substrate

low = having a broad range of targets

Question 8

Affinity

Answer 8

High = bind substrate at very low concentration
Low = will only bind substrate when it is present in high concentrations

Question 9

Molecules needed for oxidative phosphorylation:

Answer 9

1) NAD+ (derived from vitamin B3)

2) FADH+ (derived from vitamin B2)

Question 10

Glycolysis

Answer 10

Occurs in the cytosol
Breakdown of glucose (6C)
Generates 2 x molecules of pyruvate (3C)

Therefore the net yield is 8 ATP

Question 11

Where does TCA occur

Answer 11

Matrix

Question 12

Where does oxidative phosphorylation occur

Answer 12

Inner membrane

Question 13

For every glucose molecule entering TCA cycle:

Answer 13

8 x NADH
2 x FADH2
2 x ATP