13. Necrosis

Question 1

Hypertrophy

Answer 1

increase in the size of cells

Question 2

Atrophy

Answer 2

reduction in the size of cells

Question 3

Hyperplasia

Answer 3

increase in the number of cells

Question 4

Involution

Apoptosis

Answer 4

decrease in the number of cells

Question 5

Metaplasia

Answer 5

stable change from one cell type to another

Question 6

Dysplasia

Answer 6

change to an undifferentiated cell type

Question 7

Apoptosis

Answer 7

programmed cell death

Organised, energy dependant process

Question 8

Cell growth can be influenced by

Answer 8

The levels of growth factor
The levels of cell surface receptors
The levels of internal signalling pathway components

Question 9

Sub-lethal damage

cells can recover

Answer 9

Hydropic degeneration

Fatty degeneration

Question 10

Lethal damage

cells cannot recover

Answer 10

Necrosis

Question 11

Ischaemic necrosis

Answer 11

Lack of oxygen and nutrients

failure of blood supply

Question 12

Reperfusion necrosis

Answer 12

Following ischaemia no free radicals are formed
no oxygen

Free radical scavenging systems become depleted

On re-perfusion with oxygen many free radicals are formed and the depleted scavenging system is overloaded