725 Residuals

Question 1

Fluoxetine antagonizes what 5HT receptor and what does that result in?

Answer 1

5HT2C; activation

Question 2

Trazodone blocks this 5HT receptor and this results in?

Answer 2

5HT2A; sedation

Question 3

Vilazodone inhibits 5HT uptake and is also a partial _______ of 5HT_ _ which reduces the side effects of ___________ and ________.

Answer 3

agonist; 1A; sexual dysfunction and weight gain

Question 4

What atypical antidepressant is an A2 receptor antagonist and what effect does this produce?

Answer 4

mirtazapine; sedation

Question 5

What neurotransmitters does mirtazapine increase?

Answer 5

5HT and NE

Question 6

What 5HT receptor is involved in slow-wave sleep?

Answer 6

5HT2A

Question 7

TCAs block re-uptake of 5HT and NE or both and also block _____ and _____ which is responsible for many side effects.

Answer 7

H1 and A1

Question 8

TCA has an increased __________ SE due to _____ blockade and increase in _____ .

Answer 8

cardiovascular; A1; NE

Question 9

TCA’s increase neurotransmitter levels in synaptic cleft and also change _________ and intercellular __________.

Answer 9

receptors; signaling

Question 10

When the __________ ______ is damaged, this results in __________ DA which is involved in what disease?

Answer 10

nigrostriatal tract; decreased; Parkinson’s

Question 11

What mood stabilizer has the SE of pan aplastic anemia?

Answer 11

carbazepine (Tegretol)

Question 12

What “cousin” of carbazepine does not have the SE of pan aplastic anemia?

Answer 12

oxycarbazepine (Triileptal)

Question 13

What neurotransmitter is associated with the parasympathetic system?

Answer 13

Ach

Question 14

What drug is an NMDA antagonist and what neurotransmitter is increased as a result of this?

Answer 14

ketamine; glutamate

Question 15

What neurotransmitter is involved with A1, A2, B1, and B2 receptors? Where is this found in the brain?

Answer 15

NE; locus coeruleus in PONS

Question 16

What are the monoamines?

Answer 16

5HT, DA, NE

Question 17

What neurotransmitter is involved with the nicotinic and muscarinic receptors?

Answer 17

Ach

Question 18

What neurotransmitter is inactivated by an enzyme only?

Answer 18

Ach (acteylcholinerase)

Question 19

What neurotransmitter is also referred to as a noradrenergic?

Answer 19

NE

Question 20

What neurotransmitter is involved in arousal?

Answer 20

NE

Question 21

What receptor, when antagonized against, can induce seizures?

Answer 21

AMPA (glutamate receptor)