7: Muscles Flashcards
Skeletal muscle connective tissue layers
Epimysium
Perimysium
Endomysium
What’s in the epimysium
Nerves, artery’s, veins
Perimysium
Muscle fascicle
What’s in a muscle fascicle
Endomysium
Muscle fiber
What’s in a muscle fiber (8)
Nucleus/stem cell/ mitochondria
Capillaries/ axon of nerve
Sarcolemma/ sarcoplasm
Myofibrils
2 types of connective tissue attachments
Tendon- fiber bundles (muscle-bone)
Aponeurosis- fiber sheets (muscle-muscle), (muscle to flat bone)
Sarcolemma
Specialized plasma membrane
Myofibrils parts (6)
Z band A band I band Thick filament (myosin) Thin filament (actin) Sarcomere
Sarcoplasmic reticulum
Contains Ca+
Contraction cycle
- Action potential travels over Sarcolemma down into the T tubes
- Triggers release of Ca from the terminal cisternae of the sarcoplasmic Reticulum
- Ca binds to troponin which moves the tropomyosin out of the way and exposes active sites for myosin heads
3 steps to slide thin filament with thick filament
- Myosin heads of thick filament bind to active sites on thin filaments (this produces cross-bridges)
- Heads pivot toward center of sarcomere pulling the thin filament in that direction
- Cross-bridges detach and return to original position
5 steps of motor neuron stimulation of muscle fiber
- Action potential arrives at axon terminal at neuromuscular junction (AP TRAVELS THROUGH NEURON TO NEUROMUSCULAR JUNCTION)
- ACh is released and binds receptors on Sarcolemma (AP USE EXOCYTOSIS TO EXIT AXON)
- Ion permeability of Sarcolemma changes (AP BINDS TO APPROPRIATE RECEPTORS)
- Local change in membrane voltage occurs (depolarization) (AP IS IN RECEPTOR AND DEPOLARIZES TO SARCOLEMMA)
- Local depolarization ignites action potential in Sarcolemma (end of potential) (AP IS NOW IN SARCOLEMMA)
4 steps of excitation contraction coupling occurring
- Action potential travels across the entire Sarcolemma (AP TRAVELS THROUGH SARCOLEMMA)
- Action potential travels along T tubules (AP TRAVELS THROUGH T TUBULES)
- SR releases Ca which binds to the troponin and exposes myosin-binding sites (AP HITS SARCOPLASMIC MEMBRANE, RELEASES CA WHICH BIND TO TROPONIN AND MOVE TROPOMYOSIN)
- Myosin heads bind to actin and contraction behind (MYOSIN HEAD ATTACHES TO G ACTIN WITH ATP, DOES POWER STROKE, LETS GO USING ATP)
Muscle tone
Muscle are relaxed and in the contracted position
Atrophy
Muscle dies from not being stimulated by nerves
Isotonic contraction
Muscle length changes bc force applied is greater than load
Isometric contraction
Muscle length does not change because force applied is less than or equal to load
Temporalis
Assist in chewing
Frontals
Raise eyebrows
Sternocleidomastoid
Turns head side to side
Occipitals
Moves scalp back
Trapezius
Holds head up and raises shoulders
Pectoralis major
Flexes shoulder
Rectus abdominis
Flexes vertebral column
External oblique
Rotate vertebral column
Latissimus dorsi
Extends shoulders
Deltoid
Abducts shoulder
Biceps Brachii
Flexes forearm
Triceps brachii
Extends forearm
Pronator teres
Rotates forearm palm down
Flexor carpi radialis
Flexes wrist
Flexor digitorum
Flexes finger
Extensor digitorum
Extends fingers
Sartorius
Flexes the hip
Rectus femoris
Extends the knee
Tibialis anterior
Dorsiflexes foot
Name the 3 hamstrings
Biceps femoris
Semimembranosus
Semitendinous
Gastrocnemius
Plantar flexes foot
Sarcolemma
Muscle cell membrane
Sarcoplasm
Interior muscle cell fluid
Sarcomere
Z disc to z disc on a Myofibril
Sarcoplasmic reticulum
Where the Ca is stored on a myofibril
Rigor Mortis
Full muscle contraction/ stiffening of dead person
Slow fibers
Red Small Aerobic Low glycogen storage High myoglobin content Slow contraction
Fast fibers
White Large Anaerobic High glycogen Low myoglobin Fast fatigue
Cardiac cell appearance
Intercalated discs
Striated
Branched
Smooth cell appearance
Spindle shaped
Single nucleus
In organs it forms sheets, bundles, sheaths
Orients directionally per function
Skeletal cell appearance
Striated
Multinucleic