69. The general macro- and microscopic morphology of tumors. The increase in volume of tumor cells and tumoral proliferations

Question 1

Morphologic description of a tumor

Answer 1

Benign or malignant?
Soliter or multiplex
BUT: more primary tumours can occur in the same time or after each other, in the same animal
Simultaneous neoplasias can be the same in character or different, can be located in the same organ or not
Recurrence = the tumour grows back after removal None of the above is metastasis

Question 2

Colour of the tumor influenced by?

Answer 2

▪ Blood content
▪ Pigmentation
▪ Fresh or older bleeding
▪ Regressive changes (fatty infiltration, necrosis, calcification)

Question 3

2 main parts of tumor microscopic morphology

Answer 3

Stroma
Tumor parenchyma (all neoplastic cells)

Question 4

Desmoplasia

Answer 4

Tumour cells’ PDGF production induces stromal fibroblasts to produce collagene= “scirrhous” or “desmoplastic” reaction