64. Disturbances in cell division Flashcards
Normal causes of cell mitosis
Reaction to environmental stimuli (neighbouring cells)
Growth factor (GF)
Blood vessel injury
Deficient oxygen supply
Cell types of : basal epithel cell, haemoblasts, basal cells of the Lieberkühn crypts, spermatogonia
Vegetative intermitotic cells
cell types of : precursor white blood cells, spermatocytes
Differentiating intermitotic cells
cell type of: hepatocytes, tubular epithel cells of the kidney, endothelial cells, adventitial cells
Reversible postmitotic cells
Fix postmitotic cells example
neurons, erythrocytes
Endomitosis
Nuclei and cytoplasms are not separated
Polyploidia
possessing more than two complete sets of chromosomes.
Syntitial giant cells
– Several similar cells fuse
Multinucleated giant cells
– Nucleus duplicates
– Cytoplasms are not separated during mitosis
Physiological form of Multinucleated giant cells
– Osteoclasts (multinucleated)
– Placental giant cells (syntitiotrophoblast)
– Megakaryocytes (endomitosis)
Pathological cell division
Intense proliferation (Regeneration, inflammation, tumor)
Pathological form of Multinucleated giant cells
- Langhans type
– Foreign body type
– Touton type
– Syntitial giant cells
What virus can form Syntitial giant cells
Parainfluenza 3
bovine leukosis virus