6 Flashcards
where are interstitial cells of CAJAL found
musclaris propria
what junction is found between interstitial muscles of CAJAL
gap junctions
main function of interstitial muscles of cajal
depolarise spontaneously to contract and do peristalsis
whats the name of pacemaker cells
interstitial cells of CAJAL
what components make up the enteric nervous system
submucosal plexus
myenteric plexus
whats the relationship centre myenteric plexus and interstitial cells of canal
myenteric plexus modulates activity of caJAL
what ENS neurotransmission is generally excititaroy
cholinergic
excitach!!!!!!!
what ENS neurotransmission is generally inhibitory
noradrenergic
whats the migrating motor complex
pattern of electromechanical activity in GI smooth muscle between meals.
made up of 3 phases
tink of a motor bike that moves in intestine entre repas.
phase 3 is when youre most hungry.
what are the three phases of food intake
cephalic phase: preparation
gastric phase: early digestion
intestinal phase: aborption. triggered by chemoreceptor activation
whats achalasia
food blockage
movements that form the gastric phase of food intake
accommodation: stomach entry widens
receptive relaxation: relaxation of LOS
what reflex modulates gastric tone?
vasovagal reflex
whats retropulsin
allows big food chunks to be digested further
how is chyme emptied
in a linear fashion
Cholecystokinin is realsed by
duodenum and causes bile to be given to duo
how does vagus know what to do
CCK tells it what to do
explain the duodenal and jejunum brake
after high fat meal D releases CCK which tells vagus to slow down gastric ton
explain ilium break
high fat levels in ilium release PYYY GLPI to slow down stomach.
peristalsis direction
back end contracts
what neurotransmitter does the enteric nervous system release for contraction and lrelaxation
contraction: ach
relaxation: no
whats the histology of teniae carnae
3 longitudinal muscle
what the affect of 5HT3 receptor antagonists
cause constipation
as content in rectum increases what happens to the anal sphoncters
internal one relaxes
outer one contracts.
