6 Flashcards

1
Q

where are interstitial cells of CAJAL found

A

musclaris propria

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2
Q

what junction is found between interstitial muscles of CAJAL

A

gap junctions

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3
Q

main function of interstitial muscles of cajal

A

depolarise spontaneously to contract and do peristalsis

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4
Q

whats the name of pacemaker cells

A

interstitial cells of CAJAL

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5
Q

what components make up the enteric nervous system

A

submucosal plexus

myenteric plexus

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6
Q

whats the relationship centre myenteric plexus and interstitial cells of canal

A

myenteric plexus modulates activity of caJAL

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7
Q

what ENS neurotransmission is generally excititaroy

A

cholinergic

excitach!!!!!!!

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8
Q

what ENS neurotransmission is generally inhibitory

A

noradrenergic

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9
Q

whats the migrating motor complex

A

pattern of electromechanical activity in GI smooth muscle between meals.
made up of 3 phases
tink of a motor bike that moves in intestine entre repas.
phase 3 is when youre most hungry.

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10
Q

what are the three phases of food intake

A

cephalic phase: preparation
gastric phase: early digestion
intestinal phase: aborption. triggered by chemoreceptor activation

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11
Q

whats achalasia

A

food blockage

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12
Q

movements that form the gastric phase of food intake

A

accommodation: stomach entry widens

receptive relaxation: relaxation of LOS

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13
Q

what reflex modulates gastric tone?

A

vasovagal reflex

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14
Q

whats retropulsin

A

allows big food chunks to be digested further

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15
Q

how is chyme emptied

A

in a linear fashion

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16
Q

Cholecystokinin is realsed by

A

duodenum and causes bile to be given to duo

17
Q

how does vagus know what to do

A

CCK tells it what to do

18
Q

explain the duodenal and jejunum brake

A

after high fat meal D releases CCK which tells vagus to slow down gastric ton

19
Q

explain ilium break

A

high fat levels in ilium release PYYY GLPI to slow down stomach.

20
Q

peristalsis direction

A

back end contracts

21
Q

what neurotransmitter does the enteric nervous system release for contraction and lrelaxation

A

contraction: ach
relaxation: no

22
Q

whats the histology of teniae carnae

A

3 longitudinal muscle

23
Q

what the affect of 5HT3 receptor antagonists

A

cause constipation

24
Q

as content in rectum increases what happens to the anal sphoncters

A

internal one relaxes

outer one contracts.

25
Q

what mechanisms prevent defecation

A

mechanical effects of acute anorectal angle

anal sphincter and puborectalis.

26
Q

whats the initiation phase

A

when shit comes out. external anal pspincter and puborectalis relax