24 Flashcards

1
Q

boy water content for baby male female

A

80
60
50

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2
Q

what part of body absorbs the most water

A

small intestine

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3
Q

is there protein in ISF

A

no think of the banana tree on island analogy

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4
Q

is there protein in intracellular fluid

A

yes

protein anions

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5
Q

what are the major solutes that contribute to osmolality

A

electrolytes:Na Cl

non electrolytes:glucose urea

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6
Q

whats the mode of action of penicillin

A

prevent cell wall biosynthesis so cells explode

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7
Q

what can cause osmotic diarrhoea

A

lactase deficiency

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8
Q

what has a greater osmotic power electrolytes or non elxctrolyes

A

electrolytes

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9
Q

which is more commonly used osmolarity or osmolality and why

A

lality because its based on mass not volume which can change with changes in T and P.

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10
Q

normal plasma osmolality

A

300 mOsm/Kg

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11
Q

main solute in blood

A

albumin

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12
Q

what three mechanisms control sodium water regulation

A

CNS
hormones
kidneys

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13
Q

how does CNS regulate Na and sodium concentrations

A

using SFO and OVLT in hypothalamus

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14
Q

main trigger for thirst is

A

osmolality

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15
Q

how do hormones regulate plasma volume

A

ADH=vasopresin
in CD

ANP

angiotensin

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16
Q

molecular target of ADH

A

aquaporin transcription

17
Q

how do hormones regulate plasma osmolality

A

aldosterone which acts on eNAC and nak pumps
released from adrenal cortex when too little Na or too much Kplus
results in overactivatiomn of enac so takes up more sodium

18
Q

how do ANP work

A

atrial natriuretic peptide

release from cardiac atria when high blood volume
increases Na secretion.

19
Q

where is most water absorbed int eh kidney

A

80% proximal tubule

20
Q

normal urine osmolality

A

500-800 mOsm per kilo

21
Q

normal random urine osmolality

A

50-1400 mOsm per kilo

22
Q

normal urine osmolality after 12-14 hours restriction

A

more than 800 mosmoles pet kilo

23
Q

water depirivation test

A

urine osmolality after 12-14 hours restriction

24
Q

water intoxication

A

too much water drank too fast or ecstasy induced hyponatremia

25
Q

what can increase capillary permeability

A

inflammation