18

Question 1

what form do FA take in the body

Answer 1

90% TAG tryacylglycerol

10% cholesterol

Question 2

what molecules make up TAG

Answer 2

fatty acid and g3p

Question 3

how is TAG carried in the body

Answer 3

in lipoproteins

Question 4

whats lipoprotein made up of

Answer 4

outer layer: phospholipid, free cholesterol, apoprotein inner layer: TAG, cholesterol esters

Question 5

what are dietary TAG liporporis

Answer 5

packaged chyilomycrons

Question 6

how is liver derived TAG released

Answer 6

vLDL

Question 7

whats the variable part in lipoproteins

Answer 7

apoprotein

Question 8

apoprotein in chylomicron

Answer 8

B48 ACE

Question 9

apoprotein in VLDL

Answer 9

B100 ACE

Question 10

apoprotein in IDL

Answer 10

B100 E

Question 11

apoprotein in LDL

Answer 11

B100

Question 12

apoprotein in HDL

Answer 12

AI AII (CE)

Question 13

main component of chylomicron

Answer 13

TAG

Question 14

main component of VLDL

Answer 14

TAG

Question 15

main component of IDL

Answer 15

TAG cholesterol

Question 16

main component of LDL

Answer 16

cholesterol

Question 17

main component of HDL

Answer 17

protein

Question 18

why are IDL and LDL the worst

Answer 18

bc their main component is cholesterol

Question 19

whats the main function ofHDL

Answer 19

carry excess cholesterol around the body

Question 20

where is dietary fat stored

Answer 20

chylomicrons

Question 21

what do chylomicrons interact with

Answer 21

HDL which gives them ApoC2 and ApoE

ApoC2 helps unloading of fat in adipose tissue.

Question 22

how does apoc2 help unload fat in adipose tissue

Answer 22

by activating with lipoprotein lipase. and hence allowing TAG degradation into fatty acids and glycerol

Question 23

when is LPL high in adipose tissue

Answer 23

after a meal

Question 24

when is LPL high in muscle

Answer 24

during starvation

Question 25

what secretes lipoproteins

Answer 25

liver

Question 26

how does VLDL acquire its apoproteins apoc and apoE

Answer 26

from HDL

Question 27

if cells need cholesterol how do they get it

Answer 27

via LDL | which come in through apoB/E receptor on the plasma membrane

Question 28

what enzyme regulates cholesterol synthesis

Answer 28

HMG CoA reductase

Question 29

what transciprtion factor regulates expression of HMG coA reductase and LDL receptor

Answer 29

SERBIA SREBP

Question 30

where is HDL assembled

Answer 30

liver and intestine

Question 31

where does HDL cholesterol go

Answer 31

liver for extermination by bile

Question 32

what lipoprotein is cardio protective

Answer 32

HDL

Question 33

whats the ratio for risk of CVD

Answer 33

HDL/LDL

Question 34

how do statins work

Answer 34

competitive inhibitor of HMG coA reductase qui catalyse HMG coA to cholesterol

Question 35

cholestryamine

Answer 35

binds bile acid to prevent its reabsorption via enterohepatic circulation REDUCES LDL not HDL