5HT system Flashcards
1
Q
Cushing’s disease
A
constant glucocorticoid release
obesity
depression
psychosis
buffalo hump
2
Q
showerhead principle
A
one source of 5HT = raphe nucleus
gets everywhere
acts as neuromodulator
3
Q
5HT origin
A
synthesised from tryptophan
although removing it from diet only has effect in 50%
in raphe nucleus
4
Q
5HT-4 receptor
A
only expressed in gut
can be targeted
so no psychotropic effect
5
Q
third dopamine system
A
in hypothalamus
blocks lactate system
